Manteia

ENSGALG00000028770

Gallus gallus

Features

Gene ID:	ENSGALG00000028770

Biological name :	INHBB

Synonyms :	INHBB / inhibin beta B chain precursor

Possible biological names infered from orthology :	Inhibin beta B chain / inhibin beta B subunit / P09529 / Q04999

Species:	Gallus gallus

Chr. number:	7
Strand:	1
Band:
Gene start:	25714824
Gene end:	25719385

Corresponding Affymetrix probe sets:	Gga.520.1.S1_at (Chicken Array) Gga.520.2.S1_a_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000042014 NCBI entrez gene - 396126 See in Manteia. RefSeq - NM_205206 RefSeq - XM_015289788 RefSeq Peptide - NP_990537 swissprot - R4GIS0 Ensembl - ENSGALG00000028770

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*	ENSGALG00000034616	42
GDF8 / O42220 / Growth/differentiation factor 8 / MSTN* / O08689* / O14793* / myostatin*	ENSGALG00000039458	20
TGFB2 / P27090* / P61812* / transforming growth factor beta 2* / Transforming growth factor beta-2 Latency-associated peptide*	ENSGALG00000009612	19
GDF3 / embryonic growth/differentiation factor 1 / GDF1* / CERS1* / P27545* / P27544* / Q9NR23* / Q07104* / P20863* / P27539* / ceramide synthase 1* / growth differentiation factor 3* / gr...	ENSGALG00000003161	18
TGFB3 / transforming growth factor beta 3 / P10600*	ENSGALG00000010346	18
GDF10 / growth differentiation factor 10 / P55107* / P97737*	ENSGALG00000005985	16
NODAL* / P43021* / Q96S42* / nodal growth differentiation factor*	ENSGALG00000003209	15
GDF9 / growth differentiation factor 9 / O60383* / Q07105*	ENSGALG00000028407	15
BMP15 / bone morphogenetic protein 15 precursor	ENSGALG00000004742	14
BMP3 / bone morphogenetic protein 3 precursor / P12645* / Q8BHE5* / Bone morphotic protein 3 * / bone morphogenetic protein 3*	ENSGALG00000035052	14
GDF15* / Q99988* / Q9Z0J7* / growth differentiation factor 15* / Mus musculus growth differentiation factor 15 (Gdf15), transcript variant 2, mRNA.*	ENSGALG00000046278	7

Protein motifs (from Interpro)

Interpro ID	Name
IPR000381	Inhibin, beta B subunit
IPR001111	TGF-beta, propeptide
IPR001839	Transforming growth factor-beta, C-terminal
IPR006311	Twin-arginine translocation pathway, signal sequence
IPR015615	Transforming growth factor-beta-related
IPR017948	Transforming growth factor beta, conserved site
IPR029034	Cystine-knot cytokine

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0009267	cellular response to starvation	IEA
biological_process	GO:0009611	response to wounding	IEA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0032869	cellular response to insulin stimulus	IEA
biological_process	GO:0032924	activin receptor signaling pathway	IEA
biological_process	GO:0044320	cellular response to leptin stimulus	IEA
biological_process	GO:0045444	fat cell differentiation	IEA
biological_process	GO:0046676	negative regulation of insulin secretion	IEA
biological_process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	IEA
biological_process	GO:0046882	negative regulation of follicle-stimulating hormone secretion	IEA
biological_process	GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	IEA
biological_process	GO:0048599	oocyte development	IEA
biological_process	GO:0060279	positive regulation of ovulation	IEA
biological_process	GO:2001235	positive regulation of apoptotic signaling pathway	IEA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IEA
cellular_component	GO:0048471	perinuclear region of cytoplasm	IEA
cellular_component	GO:0071944	cell periphery	IEA
molecular_function	GO:0005179	hormone activity	IEA
molecular_function	GO:0008083	growth factor activity	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA

Pathways (from Reactome)

Pathway description

Signaling by Activin

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000006158	ACVR2B / activin receptor type-2B precursor / P27040* / Q13705* / Activin receptor type-2B * / activin A receptor type 2B*	/ complex / reaction
ENSGALG00000012444	ACVR2A / Q90669 / Activin receptor type-2A / P27037* / P27038* / activin A receptor type 2A*	/ complex / reaction
ENSGALG00000041257	ACVR1C / activin A receptor type 1C / Q8K348* / Q8NER5* / Activin receptor type-1C *	/ complex
ENSGALG00000028770	INHBB / inhibin beta B chain precursor / P09529* / Q04999* / Inhibin beta B chain * / inhibin beta B subunit*	/ complex
ENSGALG00000029599	ACVR1B / activin A receptor type 1B / P36896* / Q61271* / Activin receptor type-1B *	/ complex / reaction
ENSGALG00000029515	P43031 / Inhibin alpha chain / INHA* / Q04997* / P05111* / inhibin alpha subunit*	/ complex
ENSGALG00000034616	INHBA / inhibin beta A chain precursor / P08476* / Q04998* / Inhibin beta A chain * / inhibin beta A subunit*	/ complex
ENSGALG00000042356	FSTL3 / follistatin like 3 / O95633* / Q9EQC7* / Follistatin-related protein 3 *	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr