ENSGALG00000042569


Gallus gallus

Features
Gene ID: ENSGALG00000042569
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : P35831 / protein tyrosine phosphatase, non-receptor type 12 / PTPN12 / Q05209
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 12599372
Gene end: 12606519
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000044946
swissprot - A0A1D5NX53
Ensembl - ENSGALG00000042569
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPN12ENSG00000127947Homo sapiens
 P35831ENSMUSG00000028771Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPN22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSGALG0000002165651
PTPN2 / protein tyrosine phosphatase, non-receptor type 2 / P17706* / Q06180* / Tyrosine-protein phosphatase non-receptor type 2 *ENSGALG0000001386732
PTPRJ / receptor-type tyrosine-protein phosphatase eta precursor / Q12913* / protein tyrosine phosphatase, receptor type J*ENSGALG0000000638231
PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*ENSGALG0000000801031
PTPN9 / tyrosine-protein phosphatase non-receptor type 9 / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSGALG0000000166429
PTPRB / protein tyrosine phosphatase, receptor type B / B2RU80* / P23467*ENSGALG0000001004929
PTPRO / receptor-type tyrosine-protein phosphatase O / E9Q612* / Q16827* / protein tyrosine phosphatase, receptor type O*ENSGALG0000001308529
PTPRQ / protein tyrosine phosphatase, receptor type Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSGALG0000001093525
ENSGALG0000002135516
ENSGALG000000005845


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
SHC1 events in ERBB2 signaling
EGFR downregulation
Signaling by PDGF
Downregulation of ERBB2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000949 HBEGF / Q9W7C5 / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like growth factor / Q06186* / Q99075* / heparin binding EGF like growth factor*  / reaction
 ENSGALG00000002952 NRG4 / neuregulin 4 / Q8WWG1* / Q9WTX4* / Pro-neuregulin-4, membrane-bound isoform Neuregulin-4*  / reaction
 ENSGALG00000013929 PDGFRA / platelet derived growth factor receptor alpha / P16234* / P26618* / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA.*  / reaction
 ENSGALG00000003642 PDGFA / platelet derived growth factor subunit A / P04085*  / reaction
 ENSGALG00000015422 NRG1 / pro-neuregulin-1, membrane-bound isoform / Q02297* / neuregulin 1*  / reaction
 ENSGALG00000012178 PDGFB / platelet derived growth factor subunit B / P01127* / platelet derived growth factor, B polypeptide*  / reaction
 ENSGALG00000028608 BTC / probetacellulin precursor / P35070* / Q05928* / betacellulin* / Probetacellulin Betacellulin*  / reaction
 ENSGALG00000033641 NRG2 / neuregulin 2 / O14511*  / reaction
 ENSGALG00000003126 ERBB4 / receptor tyrosine-protein kinase erbB-4 / Q15303* / Q61527* / erb-b2 receptor tyrosine kinase 4* / Receptor tyrosine-protein kinase erbB-4 ERBB4 intracellular domain*  / reaction
 ENSGALG00000038089 EGFR / epidermal growth factor receptor / P00533* / Q01279*  / reaction
 ENSGALG00000039775 SHC1 / SHC adaptor protein 1 / P29353* / P98083* / SHC-transforming protein 1 *  / complex / reaction
 ENSGALG00000031529 ERBB2 / receptor tyrosine-protein kinase erbB-2 precursor / P04626* / P70424* / erb-b2 receptor tyrosine kinase 2* / Receptor tyrosine-protein kinase erbB-2 *  / reaction
 ENSGALG00000030613 PDGFRB / platelet derived growth factor receptor beta / P09619* / platelet-derived growth factor receptor beta isoform 2 *  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr