ENSMUSG00000000214


Mus musculus

Features
Gene ID: ENSMUSG00000000214
  
Biological name :Th
  
Synonyms : P24529 / Th / tyrosine hydroxylase
  
Possible biological names infered from orthology : P07101
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F5
Gene start: 142892752
Gene end: 142931128
  
Corresponding Affymetrix probe sets: 10569370 (MoGene1.0st)   1420546_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115434
Ensembl peptide - ENSMUSP00000123661
Ensembl peptide - ENSMUSP00000122876
Ensembl peptide - ENSMUSP00000122162
Ensembl peptide - ENSMUSP00000000219
Ensembl peptide - ENSMUSP00000101549
NCBI entrez gene - 21823     See in Manteia.
MGI - MGI:98735
RefSeq - NM_009377
RefSeq Peptide - NP_033403
swissprot - F6VPB5
swissprot - P24529
swissprot - E9Q9G5
swissprot - Q3UTB3
swissprot - D6RGQ9
swissprot - D3Z0B1
Ensembl - ENSMUSG00000000214
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thENSDARG00000030621Danio rerio
 THENSGALG00000029648Gallus gallus
 THENSG00000180176Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tph2 / Q8CGV2 / Tryptophan 5-hydroxylase 2 / Q8IWU9* / tryptophan hydroxylase 2*ENSMUSG0000000676446
Pah / P16331 / Phenylalanine-4-hydroxylase / P00439* / phenylalanine hydroxylase*ENSMUSG0000002005146
Tph1 / P17532 / tryptophan hydroxylase 1 / P17752*ENSMUSG0000004004644


Protein motifs (from Interpro)
Interpro ID Name
 IPR001273  Aromatic amino acid hydroxylase
 IPR005962  Tyrosine 3-monooxygenase
 IPR018301  Aromatic amino acid hydroxylase, iron/copper binding site
 IPR019773  Tyrosine 3-monooxygenase-like
 IPR019774  Aromatic amino acid hydroxylase, C-terminal
 IPR021164  Tyrosine hydroxylase, conserved site
 IPR036329  Aromatic amino acid monoxygenase, C-terminal domain superfamily
 IPR036951  Aromatic amino acid hydroxylase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001963 synaptic transmission, dopaminergic IMP
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0006585 dopamine biosynthetic process from tyrosine TAS
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0007612 learning IMP
 biological_processGO:0007613 memory IMP
 biological_processGO:0007617 mating behavior IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0008016 regulation of heart contraction IMP
 biological_processGO:0009072 aromatic amino acid family metabolic process IEA
 biological_processGO:0009414 response to water deprivation IEA
 biological_processGO:0009416 response to light stimulus IEA
 biological_processGO:0009635 response to herbicide IEA
 biological_processGO:0009651 response to salt stress IEA
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0010038 response to metal ion IEA
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0010259 multicellular organism aging IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0015842 aminergic neurotransmitter loading into synaptic vesicle IEA
 biological_processGO:0016137 glycoside metabolic process IEA
 biological_processGO:0017085 response to insecticide IEA
 biological_processGO:0018963 phthalate metabolic process IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033076 isoquinoline alkaloid metabolic process IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035900 response to isolation stress IEA
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0042136 neurotransmitter biosynthetic process IEA
 biological_processGO:0042214 terpene metabolic process IEA
 biological_processGO:0042416 dopamine biosynthetic process IEA
 biological_processGO:0042418 epinephrine biosynthetic process IEA
 biological_processGO:0042421 norepinephrine biosynthetic process IEA
 biological_processGO:0042423 catecholamine biosynthetic process IEA
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042745 circadian sleep/wake cycle IEA
 biological_processGO:0042755 eating behavior IMP
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045472 response to ether IEA
 biological_processGO:0046684 response to pyrethroid IEA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IMP
 biological_processGO:0050890 cognition IEA
 biological_processGO:0051412 response to corticosterone IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0052314 phytoalexin metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070848 response to growth factor IEA
 biological_processGO:0071287 cellular response to manganese ion IEA
 biological_processGO:0071312 cellular response to alkaloid IEA
 biological_processGO:0071316 cellular response to nicotine IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0033162 melanosome membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004511 tyrosine 3-monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008198 ferrous iron binding IEA
 molecular_functionGO:0008199 ferric iron binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016597 amino acid binding IEA
 molecular_functionGO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0019825 oxygen binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0034617 tetrahydrobiopterin binding IEA
 molecular_functionGO:0035240 dopamine binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Catecholamine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000255 vasculature congestion "obstruction of the normal flux of blood within the blood vessel network" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
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Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000279 ventricular hypoplasia "reduction in cell number of one or both of the two lower chambers of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61790]
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Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001177 atelectasis "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001246 mixed cellular infiltration to dermis "gradual accumulation of mixed cell types in the dermis that are not normally found there" [J:65416]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Thtm2Te/Thtm2Te
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001409 increased stereotypic behavior "more frequent incidence of repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, MGI:CLS, J:57125]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001412 excessive scratching "compulsive scraping of the skin, usually with the nails" [J:61340]
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Allelic Composition: Socs1tm1Ayos/Socs1tm1Ayos,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Grprtm1Jfb/Grprtm1Jfb,Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001428 adipsia "absence of thirst or lack of desire to drink " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30404]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001431 abnormal eating behavior "inability to consume or atypical consumption pattern" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:19212]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001438 aphagia "inability to eat " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30404]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001443 poor grooming "below average standard of cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [MGI:CLS, J:30404]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001454 abnormal cued conditioning behavior "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Gsx1tm1Ssp/Gsx1tm1Ssp,Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0001462 abnormal avoidance learning behavior "defects in the ability to associate a previously neutral stimulus with an unpleasant or punishing stimuli so that the animal learns to avoid the previously neutral stimulus" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001731 abnormal postnatal growth "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
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Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0001970 abnormal pain threshold "increased or decreased average level of perception of pain" [J:17792]
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Allelic Composition: Socs1tm1Ayos/Socs1tm1Ayos,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001982 reduced chemically-elicited antinociception "less than the normal analgesic effect of chemical substances" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002062 abnormal conditioning behavior "inability to change the frequency or form of a behavior as a result of the influence of the environment " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gsx1tm1Ssp/Gsx1tm1Ssp,Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002063 abnormal learning/memory/conditioning "altered ability to receive, store or recall informational stimuli" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gsx1tm1Ssp/Gsx1tm1Ssp,Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Drd2tm3.1Ebo/Drd2tm3.1Ebo,Tg(Drd1a-cre)AGsc/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: CryaaL1N/CryaaL1N,Tg(CAG-EGFP)1Osb/0
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Thtm1(cre)Te/Thtm1(cre)Te
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Thtm1(cre/Esr1)Nat/Thtm1(cre/Esr1)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0002316 anoxia "absence or almost complete absence of oxygen from inspired gases, blood, or tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0002690 akinesia "absence of movement or loss of the ability to move such as temporary or prolonged paralysis or "freezing in place"" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:82238]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002797 thigmotaxis "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0002798 abnormal active avoidance behavior "defects in the ability to escape a hostile environment to actively avoid the unpleasant or punishing stimuli ( e.g. shock) previously encountered in this environment" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Gsx1tm1Ssp/Gsx1tm1Ssp,Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002805 abnormal conditioned taste aversion behavior "a defect in the ability of an animal to learn to avoid food sources that were previously associated with aversive internal stimuli or sickness such as a drug that induces sickness " [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Gsx1tm1Ssp/Gsx1tm1Ssp,Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002822 catalepsy "a condition characterized by inactivity, lack of response to stimuli, and a tendency to maintain an immobile posture; the limbs tend to remain in whatever position they are placed (waxy rigidity); occurs with some psychoses, nervous system drug toxicity, and other conditions" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003105 abnormal heart atrium morphology "structural anomaly of one or both of the two upper chambers of the heart " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003140 dilated atria "an expansion in the volume of one or both of the upper chambers of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003224 neuron degeneration "a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0003243 abnormal dopaminergic neuron morphology "malformation or absence of the neurons that utilize dopamine as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003244 loss of dopaminergic neurons "loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003633 abnormal nervous system physiology 
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003897 abnormal ST interval "anomaly in the time between the end of S-wave and the beginning of T-wave" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

 MP:0003908 decreased stereotypic behavior "less frequent incidence of repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [RGD:Rat Genome Database submission]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003962 abnormal adrenaline level "aberrant concentration in the blood or tissues of this catacholamine hormone that stimulates the adrenergic receptors and that causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0003964 abnormal noradrenaline level "aberrant concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

Allelic Composition: Thtm1Tna/Th+
Genetic Background: B6.129-Thtm1Tna

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

Allelic Composition: Thtm2Te/Thtm2Te
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0005156 bradykinesia "decreased spontaneity and movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83301]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

Allelic Composition: Thtm2Te/Thtm2Te
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Drd2tm3.1Ebo/Drd2tm3.1Ebo,Tg(Drd1a-cre)AGsc/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0005322 abnormal serotonin level "anomalous concentration of biochemical messenger and regulator, found in the CNS, g.i. tract, and produced by platelets; it mediates neurotransmission, g.i. motility, hemostasis, and cardiovascular integrity " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Thtm2Te/Thtm2Te
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
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Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005498 hyporesponsive to tactile stimuli "reduced reflex action normally induced by touch or pain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Drd2tm3.1Ebo/Drd2tm3.1Ebo,Tg(Drd1a-cre)AGsc/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0005643 decreased dopamine level "less than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:88298]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

Allelic Composition: Thtm2Te/Thtm2Te
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Thtm1.1Ich/Thtm1.1Ich
Genetic Background: Not Specified

Allelic Composition: Thtm4.1Rpa/Thtm4.1Rpa,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008493 alpha-synuclein inclusion body "formation of aggregates of the alpha-synuclein protein in neural and glial tissue; often seen in neurodegenerative disorders such as Parkinson s disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

Allelic Composition: Psmc1tm1Maye/Psmc1tm1.1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0008504 abnormal adrenal chromaffin cell morphology "any structural anomaly of the neuroendocrine cells of the medulla of the adrenal gland that are innervated by the splanchnic nerve and that are responsible for epinephrine and norepinephrine secretion" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008788 abnormal fetal cardiomyocyte morphology "any structural anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [PMID:17429040]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008948 decreased neuron number "fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sdhdtm1Jlob/Sdhdtm2Jlob,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009750 impaired behavioral response to addictive substance "decreased sensitivity to an addictive substance capable of inducing the appearance of behavioral response, such as induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0010017 visceral vascular congestion "obstruction of the normal flux of blood within the blood vessel network of the internal organs enclosed within the cavity of the body, such as the thoracic, abdominal, endocrine, and pelvic organs" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0010019 liver vascular congestion "obstruction of the normal flux of blood within the blood vessel network of the liver" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010021 heart vascular congestion "obstruction of the normal flux of blood within the blood vessel network of the heart" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0010072 increased pruritus "abnormal presence or increased intensity of an uncomfortable sensation resulting from irritation of the skin or mucous membranes that evokes the desire or reflex to rub or scratch" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Slc17a6tm1Kldr/Slc17a6tm1Kldr,Thtm1(cre)Te/Th+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Psmc1tm1Maye/Psmc1tm1Maye,Thtm1(cre)Te/Th+
Genetic Background: involves: 129X1/SvJ * CD-1

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: CryaaL1N/CryaaL1N,Tg(CAG-EGFP)1Osb/0
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

Allelic Composition: Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Thtm1Tna/Thtm1Tna
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)

Allelic Composition: Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Thtm2Rpa/Thtm2Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011939 increased food intake "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0011940 decreased food intake "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0011957 decreased compensatory feeding amount "decreased amount of food consumed after a period of fasting" [MGI:csmith]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm1Rpa/Thtm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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