ENSGALG00000029648


Gallus gallus

Features
Gene ID: ENSGALG00000029648
  
Biological name :TH
  
Synonyms : TH / tyrosine hydroxylase
  
Possible biological names infered from orthology : P07101 / P24529
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 13714517
Gene end: 13730918
  
Corresponding Affymetrix probe sets: Gga.327.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051175
NCBI entrez gene - 395592     See in Manteia.
RefSeq - NM_204805
RefSeq Peptide - NP_990136
swissprot - Q9PU40
Ensembl - ENSGALG00000029648
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thENSDARG00000030621Danio rerio
 THENSG00000180176Homo sapiens
 ThENSMUSG00000000214Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001930055
TPH1 / P70080 / Tryptophan 5-hydroxylase 1 / P17752* / P17532* / tryptophan hydroxylase 1*ENSGALG0000000623647
TPH2 / tryptophan hydroxylase 2 / Q8CGV2* / Q8IWU9* / Tryptophan 5-hydroxylase 2 *ENSGALG0000001019847
PAH / phenylalanine hydroxylase / P00439* / P16331* / Phenylalanine-4-hydroxylase *ENSGALG0000001275447


Protein motifs (from Interpro)
Interpro ID Name
 IPR001273  Aromatic amino acid hydroxylase
 IPR005962  Tyrosine 3-monooxygenase
 IPR018301  Aromatic amino acid hydroxylase, iron/copper binding site
 IPR019773  Tyrosine 3-monooxygenase-like
 IPR019774  Aromatic amino acid hydroxylase, C-terminal
 IPR021164  Tyrosine hydroxylase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001963 synaptic transmission, dopaminergic IEA
 biological_processGO:0006585 dopamine biosynthetic process from tyrosine IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007617 mating behavior IEA
 biological_processGO:0007619 courtship behavior ISS
 biological_processGO:0007625 grooming behavior ISS
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008016 regulation of heart contraction IEA
 biological_processGO:0009072 aromatic amino acid family metabolic process IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0035176 social behavior ISS
 biological_processGO:0042416 dopamine biosynthetic process IEA
 biological_processGO:0042418 epinephrine biosynthetic process IEA
 biological_processGO:0042421 norepinephrine biosynthetic process IEA
 biological_processGO:0042423 catecholamine biosynthetic process IEA
 biological_processGO:0042462 eye photoreceptor cell development IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IEA
 biological_processGO:0051705 multi-organism behavior ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060416 response to growth hormone IMP
 biological_processGO:0071625 vocalization behavior ISS
 cellular_componentGO:0005623 cell ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0033162 melanosome membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004511 tyrosine 3-monooxygenase activity IDA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Catecholamine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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