ENSMUSG00000000794


Mus musculus

Features
Gene ID: ENSMUSG00000000794
  
Biological name :Kcnn3
  
Synonyms : Kcnn3 / P58391 / Small conductance calcium-activated potassium channel protein 3
  
Possible biological names infered from orthology : potassium calcium-activated channel subfamily N member 3 / Q9UGI6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 89520164
Gene end: 89675132
  
Corresponding Affymetrix probe sets: 10493555 (MoGene1.0st)   1421632_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000811
NCBI entrez gene - 140493     See in Manteia.
MGI - MGI:2153183
RefSeq - NM_080466
RefSeq Peptide - NP_536714
swissprot - P58391
Ensembl - ENSMUSG00000000794
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNN3ENSGALG00000030554Gallus gallus
 KCNN3ENSG00000143603Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnn2 / P58390 / potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 / Q9H2S1* / potassium calcium-activated channel subfamily N member 2*ENSMUSG0000005447758
Kcnn1 / potassium calcium-activated channel subfamily N member 1 / Q92952*ENSMUSG0000000290848
Kcnn4 / O89109 / potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 / O15554* / potassium calcium-activated channel subfamily N member 4*ENSMUSG0000005434226


Protein motifs (from Interpro)
Interpro ID Name
 IPR004178  Calmodulin-binding domain
 IPR013099  Potassium channel domain
 IPR015449  Potassium channel, calcium-activated, SK
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036122  SK, calmodulin-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043025 neuronal cell body IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0016286 small conductance calcium-activated potassium channel activity IBA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001957 apnea "absence of breathing; sometimes episodic" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17384]
Show

Allelic Composition: Sema3cL605P/Sema3c+
Genetic Background: C57BL/6J-Sema3cL605P

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chd7Ome/Chd7+
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0005572 abnormal breathing frequency "deviation from the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Sema3cL605P/Sema3c+
Genetic Background: C57BL/6J-Sema3cL605P

 MP:0008028 pregnancy-related premature death "death occuring before the normal life span of an organism, occuring during pregnancy, parturition or lactation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sema3cL605P/Sema3c+
Genetic Background: C57BL/6J-Sema3cL605P

 MP:0012010 parturition failure "the process of labor and delivery in female animals does not initiate or complete" [MGI:csmith]
Show

Allelic Composition: Sema3cL605P/Sema3c+
Genetic Background: C57BL/6J-Sema3cL605P

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000794 Kcnn3 / P58391 / Small conductance calcium-activated potassium channel protein 3 / Q9UGI6* / potassium calcium-activated channel subfamily N member 3*  / complex
 ENSMUSG00000054477 Kcnn2 / P58390 / potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 / Q9H2S1* / potassium calcium-activated channel subfamily N member 2*  / complex






 

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