| MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2m1Btlr/Kcnn2m1Btlr
Genetic Background: C57BL/6J-Kcnn2m1Btlr
Allelic Composition: Kcnn2bc-8J/Kcnn2bc-8J
Genetic Background: C57BL/6J-bc8J/GrsrJ
Allelic Composition: Kcnn2bc-9J/Kcnn2bc-9J
Genetic Background: C57BL/6J-bc9J/GrsrJ
Allelic Composition: Kcnn2bc-4J/Kcnn2bc-4J
Genetic Background: C57BL/6By
Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-5J
Genetic Background: (C3H/HeSn-bc3J x LP/J-bc5J)F1
Allelic Composition: Kcnn2bc-7J/Kcnn2bc-7J
Genetic Background: B6.Cg-Kcnn2bc-7J/GrsrJ
Allelic Composition: Kcnn2bc-6J/Kcnn2bc-6J
Genetic Background: C57BL/6J-Kcnn2bc-6J/GrsrJ
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Otx2tm5(OTX2)Asim/Otx2tm5(OTX2)Asim
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2m1Btlr/Kcnn2m1Btlr
Genetic Background: C57BL/6J-Kcnn2m1Btlr
Allelic Composition: Kcnn2bc-8J/Kcnn2bc-8J
Genetic Background: C57BL/6J-bc8J/GrsrJ
Allelic Composition: Kcnn2bc-9J/Kcnn2bc-9J
Genetic Background: C57BL/6J-bc9J/GrsrJ
Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
Allelic Composition: Kcnn2bc-7J/Kcnn2bc-7J
Genetic Background: B6.Cg-Kcnn2bc-7J/GrsrJ
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| MP:0001392 | abnormal locomotor activity | "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cav1tm1Pesch/Cav1tm1Pesch,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: FVB.Cg-Cav1tm1Pesch Speer6-ps1Tg(Alb-cre)21Mgn
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| MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Kcnn2bc-8J/Kcnn2bc-8J
Genetic Background: C57BL/6J-bc8J/GrsrJ
Allelic Composition: Kcnn2bc-9J/Kcnn2bc-9J
Genetic Background: C57BL/6J-bc9J/GrsrJ
Allelic Composition: Kcnn2bc-7J/Kcnn2bc-7J
Genetic Background: B6.Cg-Kcnn2bc-7J/GrsrJ
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| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2m1Btlr/Kcnn2m1Btlr
Genetic Background: C57BL/6J-Kcnn2m1Btlr
Allelic Composition: Kcnn2bc-4J/Kcnn2bc-4J
Genetic Background: C57BL/6By
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-5J
Genetic Background: (C3H/HeSn-bc3J x LP/J-bc5J)F1
Allelic Composition: Kcnn2bc-6J/Kcnn2bc-6J
Genetic Background: C57BL/6J-Kcnn2bc-6J/GrsrJ
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| MP:0001407 | short stride length | "reduced average distance between steps" [J:34193] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0001454 | abnormal cued conditioning behavior | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0001463 | abnormal spatial learning | "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0001469 | abnormal contextual conditioning | "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0001473 | reduced long term potentiation | "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0001505 | hunched posture | "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404] |
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Allelic Composition: Kcnn2m1Btlr/Kcnn2m1Btlr
Genetic Background: C57BL/6J-Kcnn2m1Btlr
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| MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kcnn2m1Btlr/Kcnn2m1Btlr
Genetic Background: C57BL/6J-Kcnn2m1Btlr
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| MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0001524 | impaired limb coordination | "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2bc-4J/Kcnn2bc-4J
Genetic Background: C57BL/6By
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-5J
Genetic Background: (C3H/HeSn-bc3J x LP/J-bc5J)F1
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| MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2bc-7J/Kcnn2bc-7J
Genetic Background: B6.Cg-Kcnn2bc-7J/GrsrJ
Allelic Composition: Kcnn2bc-6J/Kcnn2bc-6J
Genetic Background: C57BL/6J-Kcnn2bc-6J/GrsrJ
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdh23v-2J/Cdh23+,Pcdh15av-3J/Pcdh15+
Genetic Background: C57BL/6J-Cdh23v-2J Pcdh15av-3J
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| MP:0002206 | abnormal CNS synaptic transmission | "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0002566 | abnormal sexual interaction | "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkaa2tm1Vio/Prkaa2tm1Vio,Tg(Agrp-cre)1Gsb/0
Genetic Background: involves: 129S2/SvPas * FVB/N
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| MP:0002757 | reduced vertical activity | "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0002800 | abnormal short-term recognition memory | "defects in the short-term memory for objects is established during the first few minutes after training" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0002912 | abnormal excitatory postsynaptic potential | "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0003312 | abnormal locomotor coordination | "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
Allelic Composition: Kcnn2bc-4J/Kcnn2bc-4J
Genetic Background: C57BL/6By
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| MP:0003412 | abnormal afterhyperpolarization | "anomaly in the currents that follow an action potential and influence firing frequency and neuronal integration" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94941] |
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Allelic Composition: Sim1tm1.1Az/Sim1+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB
Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
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| MP:0003463 | abnormal single cell response | "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission] |
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Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
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| MP:0003492 | abnormal involuntary movement | "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission] |
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Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
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| MP:0005402 | abnormal action potential | "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sim1tm1.1Az/Sim1+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB
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| MP:0008026 | abnormal brain white matter morphology | "any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0008027 | abnormal spinal cord white matter morphology | "any structural anomaly of the regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fasntm1Sem/Fasntm1Sem,Tg(Ins2-cre)25Mgn/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA
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| MP:0008874 | decreased sensitivity to xenobiotics | "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kcnn2fri/Kcnn2fri
Genetic Background: 129S2.C3Pas-Kcnn2fri
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Kcnn2bc/Kcnn2bc
Genetic Background: Not Specified
Allelic Composition: Kcnn2bc-2J/Kcnn2bc-2J
Genetic Background: C57BL/6J-Kcnn2bc2J
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Shhtm2Amc/Shhtm2Amc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Kcnn2bc-6J/Kcnn2bc-6J
Genetic Background: C57BL/6J-Kcnn2bc-6J/GrsrJ
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| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Kcnn2bc-3J/Kcnn2bc-3J
Genetic Background: C3H/HeSn-bc3J
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