ENSMUSG00000001227


Mus musculus

Features
Gene ID: ENSMUSG00000001227
  
Biological name :Sema6b
  
Synonyms : O54951 / Sema6b / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
  
Possible biological names infered from orthology : Q9H3T3 / semaphorin 6B
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 56123085
Gene end: 56140343
  
Corresponding Affymetrix probe sets: 10451955 (MoGene1.0st)   10451974 (MoGene1.0st)   1448790_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001256
Ensembl peptide - ENSMUSP00000130985
NCBI entrez gene - 20359     See in Manteia.
MGI - MGI:1202889
RefSeq - XM_006523930
RefSeq - NM_001130456
RefSeq - NM_013662
RefSeq Peptide - NP_038690
RefSeq Peptide - NP_001123928
swissprot - O54951
swissprot - Q3UTK5
Ensembl - ENSMUSG00000001227
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sema6baENSDARG00000036626Danio rerio
 sema6bbENSDARG00000061976Danio rerio
 SEMA6BENSGALG00000001171Gallus gallus
 Q9H3T3ENSG00000167680Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O35464 / Sema6a / Semaphorin-6A / Q9H2E6*ENSMUSG0000001964748
Q76KF0 / Sema6d / Semaphorin-6D / Q8NFY4*ENSMUSG0000002720040
Q9WTM3 / Sema6c / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C / Q9H3T2* / semaphorin 6C*ENSMUSG0000003877736
Q60519 / Sema5b / Semaphorin-5B / Q9P283*ENSMUSG0000005213327
Sema5a / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A / Q13591* / semaphorin 5A*ENSMUSG0000002223125
Q9QUR8 / Sema7a / Semaphorin-7A / O75326* / semaphorin 7A (John Milton Hagen blood group)*ENSMUSG0000003826415


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR027231  Semaphorin
 IPR036352  Sema domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030215 semaphorin receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002761 abnormal hippocampal mossy fiber morphology "absence or misprojection of axons of neuronal cells in the dentate gyrus" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:4978]
Show

Allelic Composition: Git2Gt(XG510)Byg/Git2Gt(XG510)Byg,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6

Allelic Composition: Plxna2tm1Hfu/Plxna2tm1Hfu,Sema6btm1Hfu/Sema6btm1Hfu
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

Allelic Composition: Plxna2tm1Hfu/Plxna2tm1Hfu,Sema6btm1Hfu/Sema6b+
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

Allelic Composition: Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg,Sema6btm1Hfu/Sema6btm1Hfu
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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