ENSMUSG00000004609


Mus musculus

Features
Gene ID: ENSMUSG00000004609
  
Biological name :Cd33
  
Synonyms : Cd33 / Myeloid cell surface antigen CD33 / Q63994
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 43524216
Gene end: 43544428
  
Corresponding Affymetrix probe sets: 10562709 (MoGene1.0st)   1450513_at (Mouse Genome 430 2.0 Array)   1456893_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146225
Ensembl peptide - ENSMUSP00000004728
Ensembl peptide - ENSMUSP00000045458
Ensembl peptide - ENSMUSP00000145596
NCBI entrez gene - 12489     See in Manteia.
MGI - MGI:99440
RefSeq - XM_006540590
RefSeq - NM_001111058
RefSeq - NM_021293
RefSeq Peptide - NP_001104528
RefSeq Peptide - NP_067268
swissprot - Q63994
swissprot - A0A0U1RNJ9
Ensembl - ENSMUSG00000004609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q920G3 / Siglec5 / Sialic acid-binding Ig-like lectin 5 ENSMUSG0000003901337
Q91Y57 / Siglece / Sialic acid-binding Ig-like lectin 12 / Q9Y286* / Q9Y336* / Q9NYZ4* / Q96PQ1* / SIGLEC7* / SIGLEC8* / SIGLEC9* / SIGLEC12* / sialic acid binding Ig like lectin 7* / sial...ENSMUSG0000003047434
Siglech / sialic acid binding Ig-like lectin H / CD33* / P20138* / CD33 molecule*ENSMUSG0000005150433
Q80ZE3 / Siglecg / Sialic acid-binding Ig-like lectin 10 / Q96RL6* / Q96LC7* / SIGLEC10* / SIGLEC11* / sialic acid binding Ig like lectin 11*ENSMUSG0000003046826
Mag / P20917 / Mus musculus myelin-associated glycoprotein (Mag), transcript variant 5, mRNA. / P20916* / myelin associated glycoprotein*ENSMUSG0000003663418


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001586 abnormal erythrocyte count "altered number of red blood cells per volume in the bloodstream" [J:53370]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Fn1tm2Feb/Fn1tm2Feb
Genetic Background: involves: 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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