ENSMUSG00000039013


Mus musculus

Features
Gene ID: ENSMUSG00000039013
  
Biological name :Siglec5
  
Synonyms : Q920G3 / Sialic acid-binding Ig-like lectin 5 / Siglec5
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 43351341
Gene end: 43359531
  
Corresponding Affymetrix probe sets: 10552369 (MoGene1.0st)   1424975_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000012798
Ensembl peptide - ENSMUSP00000112583
Ensembl peptide - ENSMUSP00000113245
Ensembl peptide - ENSMUSP00000146009
NCBI entrez gene - 233186     See in Manteia.
MGI - MGI:2681107
RefSeq - XM_006540816
RefSeq - NM_001271019
RefSeq - NM_145581
RefSeq Peptide - NP_001257948
RefSeq Peptide - NP_663556
swissprot - Q80ZE2
swissprot - Q920G3
swissprot - B7ZN64
Ensembl - ENSMUSG00000039013
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80ZE3 / Siglecg / Sialic acid-binding Ig-like lectin 10 / Q96RL6* / Q96LC7* / SIGLEC10* / SIGLEC11* / sialic acid binding Ig like lectin 11*ENSMUSG0000003046838
Q91Y57 / Siglece / Sialic acid-binding Ig-like lectin 12 / Q9Y286* / Q9Y336* / Q9NYZ4* / Q96PQ1* / SIGLEC7* / SIGLEC8* / SIGLEC9* / SIGLEC12* / sialic acid binding Ig like lectin 7* / sial...ENSMUSG0000003047433
Cd33 / Q63994 / Myeloid cell surface antigen CD33 ENSMUSG0000000460927
Siglech / sialic acid binding Ig-like lectin H / CD33* / P20138* / CD33 molecule*ENSMUSG0000005150425
Mag / P20917 / Mus musculus myelin-associated glycoprotein (Mag), transcript variant 5, mRNA. / P20916* / myelin associated glycoprotein*ENSMUSG0000003663421


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0048029 monosaccharide binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002443 abnormal eosinophil morphology/development "anomalous structure, differentiation or number of the granular leukocytes having a two-lobed nucleus and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002465 abnormal eosinophil physiology "abnormal function of the leukocyte that stains with eosin and is involved in clearance of parasitic infections and in allergic reactions " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005011 increased eosinophil count "greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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