ENSMUSG00000014351


Mus musculus

Features
Gene ID: ENSMUSG00000014351
  
Biological name :Gip
  
Synonyms : Gastric inhibitory polypeptide / Gip / P48756
  
Possible biological names infered from orthology : P09681
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 96024545
Gene end: 96030831
  
Corresponding Affymetrix probe sets: 10380581 (MoGene1.0st)   1449908_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099445
Ensembl peptide - ENSMUSP00000099446
NCBI entrez gene - 14607     See in Manteia.
MGI - MGI:107504
RefSeq - XM_006532225
RefSeq - NM_008119
RefSeq - XM_006532224
RefSeq Peptide - NP_032145
swissprot - P48756
Ensembl - ENSMUSG00000014351
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GIPENSG00000159224Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000532  Glucagon/GIP/secretin/VIP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007613 memory IDA
 biological_processGO:0008344 adult locomotory behavior IDA
 biological_processGO:0009743 response to carbohydrate IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010269 response to selenium ion IEA
 biological_processGO:0010447 response to acidic pH IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010828 positive regulation of glucose transmembrane transport IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0019233 sensory perception of pain IDA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0033993 response to lipid IEA
 biological_processGO:0035640 exploration behavior IDA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling IEA
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IEA
 biological_processGO:0055123 digestive system development IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 biological_processGO:0070094 positive regulation of glucagon secretion IEA
 biological_processGO:0070328 triglyceride homeostasis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Arxtm5Kki/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021587 Pcsk1 / P63239 / Neuroendocrine convertase 1 / P29120* / proprotein convertase subtilisin/kexin type 1*  / reaction
 ENSMUSG00000035000 Dpp4 / P28843 / Dipeptidyl peptidase 4 Dipeptidyl peptidase 4 membrane form Dipeptidyl peptidase 4 soluble form / P27487* / dipeptidyl peptidase 4*  / reaction
 ENSMUSG00000030406 Gipr / Q0P543 / Gastric inhibitory polypeptide receptor / P48546*  / complex / reaction






 

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