ENSMUSG00000014725


Mus musculus

Features
Gene ID: ENSMUSG00000014725
  
Biological name :Adam28
  
Synonyms : Adam28 / Disintegrin and metalloproteinase domain-containing protein 28 / Q9JLN6
  
Possible biological names infered from orthology : ADAM metallopeptidase domain 28 / Q9UKQ2
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D1
Gene start: 68606027
Gene end: 68655842
  
Corresponding Affymetrix probe sets: 10421143 (MoGene1.0st)   1452495_at (Mouse Genome 430 2.0 Array)   1460427_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022642
Ensembl peptide - ENSMUSP00000106701
Ensembl peptide - ENSMUSP00000153354
Ensembl peptide - ENSMUSP00000155362
NCBI entrez gene - 13522     See in Manteia.
MGI - MGI:105988
RefSeq - XM_017315836
RefSeq - NM_001048175
RefSeq - NM_010082
RefSeq - NM_183366
RefSeq - XM_006518514
RefSeq Peptide - NP_899222
RefSeq Peptide - NP_001041640
RefSeq Peptide - NP_034212
swissprot - Q9JLN6
Ensembl - ENSMUSG00000014725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam28ENSDARG00000035514Danio rerio
 ADAM28ENSG00000042980Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adam8 / Q05910 / Disintegrin and metalloproteinase domain-containing protein 8 / P78325* / ADAM metallopeptidase domain 8*ENSMUSG0000002547337
Adam7 / O35227 / Disintegrin and metalloproteinase domain-containing protein 7 / Q9H2U9* / ADAM metallopeptidase domain 7*ENSMUSG0000002205634
Adam12 / Q61824 / Disintegrin and metalloproteinase domain-containing protein 12 / O43184* / ADAM metallopeptidase domain 12*ENSMUSG0000005455532
Adam19 / O35674 / Disintegrin and metalloproteinase domain-containing protein 19 / Q9H013* / ADAM metallopeptidase domain 19*ENSMUSG0000001125631
Adam33 / Q923W9 / Disintegrin and metalloproteinase domain-containing protein 33 / Q9BZ11* / ADAM metallopeptidase domain 33*ENSMUSG0000002731829
Adam15 / O88839 / Disintegrin and metalloproteinase domain-containing protein 15 / Q13444* / ADAM metallopeptidase domain 15*ENSMUSG0000002804129
Adam22 / Q9R1V6 / Disintegrin and metalloproteinase domain-containing protein 22 / Q9P0K1* / ADAM metallopeptidase domain 22*ENSMUSG0000004053726
Adam23 / Q9R1V7 / Disintegrin and metalloproteinase domain-containing protein 23 / O75077* / ADAM metallopeptidase domain 23*ENSMUSG0000002596424
Adam11 / Q9R1V4 / Disintegrin and metalloproteinase domain-containing protein 11 / O75078* / ADAM metallopeptidase domain 11*ENSMUSG0000002092623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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