ENSMUSG00000027318


Mus musculus

Features
Gene ID: ENSMUSG00000027318
  
Biological name :Adam33
  
Synonyms : Adam33 / Disintegrin and metalloproteinase domain-containing protein 33 / Q923W9
  
Possible biological names infered from orthology : ADAM metallopeptidase domain 33 / Q9BZ11
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 131050591
Gene end: 131063814
  
Corresponding Affymetrix probe sets: 10487797 (MoGene1.0st)   1444628_at (Mouse Genome 430 2.0 Array)   1451904_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139366
Ensembl peptide - ENSMUSP00000122608
Ensembl peptide - ENSMUSP00000139344
Ensembl peptide - ENSMUSP00000052486
Ensembl peptide - ENSMUSP00000105861
Ensembl peptide - ENSMUSP00000117097
NCBI entrez gene - 110751     See in Manteia.
MGI - MGI:1341813
RefSeq - XM_011239255
RefSeq - NM_033615
RefSeq - XM_006498576
RefSeq - XM_011239248
RefSeq - XM_011239249
RefSeq - XM_011239250
RefSeq - XM_011239251
RefSeq - XM_011239252
RefSeq - NM_001163529
RefSeq Peptide - NP_291093
RefSeq Peptide - NP_001157001
swissprot - V9GXX4
swissprot - F7CIM2
swissprot - Q923W9
swissprot - A2AP51
swissprot - F6Z4C4
Ensembl - ENSMUSG00000027318
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam19aENSDARG00000059693Danio rerio
 ADAM33ENSGALG00000030602Gallus gallus
 ADAM33ENSG00000149451Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adam19 / O35674 / Disintegrin and metalloproteinase domain-containing protein 19 / Q9H013* / ADAM metallopeptidase domain 19*ENSMUSG0000001125642
Adam12 / Q61824 / Disintegrin and metalloproteinase domain-containing protein 12 / O43184* / ADAM metallopeptidase domain 12*ENSMUSG0000005455541
Adam15 / O88839 / Disintegrin and metalloproteinase domain-containing protein 15 / Q13444* / ADAM metallopeptidase domain 15*ENSMUSG0000002804134
Adam8 / Q05910 / Disintegrin and metalloproteinase domain-containing protein 8 / P78325* / ADAM metallopeptidase domain 8*ENSMUSG0000002547332
Adam28 / Q9JLN6 / Disintegrin and metalloproteinase domain-containing protein 28 / Q9UKQ2* / ADAM metallopeptidase domain 28*ENSMUSG0000001472529
Adam11 / Q9R1V4 / Disintegrin and metalloproteinase domain-containing protein 11 / O75078* / ADAM metallopeptidase domain 11*ENSMUSG0000002092629
Adam23 / Q9R1V7 / Disintegrin and metalloproteinase domain-containing protein 23 / O75077* / ADAM metallopeptidase domain 23*ENSMUSG0000002596428
Adam22 / Q9R1V6 / Disintegrin and metalloproteinase domain-containing protein 22 / Q9P0K1* / ADAM metallopeptidase domain 22*ENSMUSG0000004053727
Adam7 / O35227 / Disintegrin and metalloproteinase domain-containing protein 7 / Q9H2U9* / ADAM metallopeptidase domain 7*ENSMUSG0000002205624


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis NAS
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0042035 regulation of cytokine biosynthetic process NAS
 biological_processGO:0042127 regulation of cell proliferation NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0004222 metalloendopeptidase activity NAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Elntm1Dyl/Eln+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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