ENSMUSG00000016128


Mus musculus

Features
Gene ID: ENSMUSG00000016128
  
Biological name :Stard13
  
Synonyms : Q923Q2 / Stard13 / StAR-related lipid transfer protein 13
  
Possible biological names infered from orthology : Q9Y3M8 / StAR related lipid transfer domain containing 13
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G3
Gene start: 151037510
Gene end: 151233836
  
Corresponding Affymetrix probe sets: 10535956 (MoGene1.0st)   1452604_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144056
Ensembl peptide - ENSMUSP00000106109
Ensembl peptide - ENSMUSP00000116705
Ensembl peptide - ENSMUSP00000122468
Ensembl peptide - ENSMUSP00000053232
NCBI entrez gene - 243362     See in Manteia.
MGI - MGI:2385331
RefSeq - XM_006504925
RefSeq - NM_001163493
RefSeq - NM_146258
RefSeq - XM_006504918
RefSeq - XM_006504920
RefSeq - XM_006504921
RefSeq - XM_006504922
RefSeq - XM_006504923
RefSeq Peptide - NP_001156965
RefSeq Peptide - NP_666370
swissprot - D3Z418
swissprot - D3Z5Y1
swissprot - A0A0J9YU82
swissprot - Q923Q2
swissprot - F8WIY7
Ensembl - ENSMUSG00000016128
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stard13aENSDARG00000079542Danio rerio
 stard13bENSDARG00000098954Danio rerio
 STARD13ENSGALG00000017065Gallus gallus
 Q9Y3M8ENSG00000133121Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dlc1 / DLC1 Rho GTPase activating protein / Q96QB1*ENSMUSG0000003152353
Q8K031 / Stard8 / StAR-related lipid transfer protein 8 / Q92502* / StAR related lipid transfer domain containing 8*ENSMUSG0000003121640
O54834 / Arhgap6 / Rho GTPase activating protein 6 / O43182*ENSMUSG0000003135513
Q8K0Q5 / Arhgap18 / Rho GTPase-activating protein 18 / Q8N392*ENSMUSG0000003903112
Q8BN58 / Arhgap28 / Mus musculus Rho GTPase activating protein 28 (Arhgap28), transcript variant 2, mRNA. / Q9P2N2* / Rho GTPase activating protein 28*ENSMUSG0000002404311
E9Q6X9 / Arhgap40 / Rho GTPase-activating protein 40 / Q5TG30*ENSMUSG0000007462510
B1AUC7 / Arhgap36 / Mus musculus Rho GTPase activating protein 36 (Arhgap36), transcript variant 2, mRNA. / Q6ZRI8* / Rho GTPase activating protein 36*ENSMUSG000000361988
Q80Y19 / Arhgap11a / Rho GTPase-activating protein 11A / Q6P4F7*ENSMUSG000000412198
Gm42906ENSMUSG000001070114


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001660  Sterile alpha motif domain
 IPR002913  START domain
 IPR008936  Rho GTPase activation protein
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR023393  START-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:0097498 endothelial tube lumen extension IEA
 biological_processGO:1903671 negative regulation of sprouting angiogenesis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Spns2tm1a(KOMP)Wtsi/Wtsi

Allelic Composition: Stard13tm1a(KOMP)Wtsi/Stard13tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0000688 lymphoid hyperplasia "increased cell number in lymphatic tissues" [J:62478]
Show

Allelic Composition: Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Slc34a1tm1Hten/Slc34a1tm1Hten,Slc34a3tm1Kimi/Slc34a3tm1Kimi
Genetic Background: B6.129-Slc34a3tm1Kimi Slc34a1tm1Hten

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Slc34a1tm1Hten/Slc34a1tm1Hten,Slc34a3tm1Kimi/Slc34a3tm1Kimi
Genetic Background: B6.129-Slc34a3tm1Kimi Slc34a1tm1Hten

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Stard13tm1a(KOMP)Wtsi/Stard13tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0003721 increased tumor growth/size "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Aestm1.1Mmt/Aestm1.1Mmt,Apctm1Mmt/Apc+,Tg(Vil-cre/ERT2)23Syr/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA * SJL

 MP:0003934 abnormal pancreas development "anomaly in the formation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Stard13tm1.2Fms/Stard13tm1.2Fms
Genetic Background: involves: BALB/cJ * C57BL/6 * SJL

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005601 increased angiogenesis "enhanced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Aestm1.1Mmt/Aestm1.1Mmt,Apctm1Mmt/Apc+,Tg(Vil-cre/ERT2)23Syr/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA * SJL

 MP:0009111 pancreas hypoplasia "underdevelopment or reduced size of the pancreas, usually due to a reduced number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc34a1tm1Hten/Slc34a1tm1Hten,Slc34a3tm1Kimi/Slc34a3tm1Kimi
Genetic Background: B6.129-Slc34a3tm1Kimi Slc34a1tm1Hten

 MP:0010144 abnormal tumor vascularization "aberrant process of blood vessel formation and the subsequent remodeling process within and/or around tumors" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aestm1.1Mmt/Aestm1.1Mmt,Apctm1Mmt/Apc+,Tg(Vil-cre/ERT2)23Syr/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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