ENSMUSG00000039031


Mus musculus

Features
Gene ID: ENSMUSG00000039031
  
Biological name :Arhgap18
  
Synonyms : Arhgap18 / Q8K0Q5 / Rho GTPase-activating protein 18
  
Possible biological names infered from orthology : Q8N392
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: A4
Gene start: 26753421
Gene end: 26918648
  
Corresponding Affymetrix probe sets: 10362294 (MoGene1.0st)   1426952_at (Mouse Genome 430 2.0 Array)   1431133_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044834
Ensembl peptide - ENSMUSP00000135030
Ensembl peptide - ENSMUSP00000135783
NCBI entrez gene - 73910     See in Manteia.
MGI - MGI:1921160
RefSeq - XM_006512885
RefSeq - NM_176837
RefSeq Peptide - NP_789807
swissprot - H3BJL1
swissprot - Q8K0Q5
swissprot - H3BLG9
Ensembl - ENSMUSG00000039031
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap18ENSDARG00000074740Danio rerio
 ARHGAP18ENSGALG00000031843Gallus gallus
 Q8N392ENSG00000146376Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BN58 / Arhgap28 / Mus musculus Rho GTPase activating protein 28 (Arhgap28), transcript variant 2, mRNA. / Q9P2N2* / Rho GTPase activating protein 28*ENSMUSG0000002404341
E9Q6X9 / Arhgap40 / Rho GTPase-activating protein 40 / Q5TG30*ENSMUSG0000007462535
Dlc1 / DLC1 Rho GTPase activating protein / Q96QB1*ENSMUSG0000003152321
Q923Q2 / Stard13 / StAR-related lipid transfer protein 13 / Q9Y3M8* / StAR related lipid transfer domain containing 13*ENSMUSG0000001612820
Q8K031 / Stard8 / StAR-related lipid transfer protein 8 / Q92502* / StAR related lipid transfer domain containing 8*ENSMUSG0000003121618
O54834 / Arhgap6 / Rho GTPase activating protein 6 / O43182*ENSMUSG0000003135518
Q80Y19 / Arhgap11a / Rho GTPase-activating protein 11A / Q6P4F7*ENSMUSG0000004121914
B1AUC7 / Arhgap36 / Mus musculus Rho GTPase activating protein 36 (Arhgap36), transcript variant 2, mRNA. / Q6ZRI8* / Rho GTPase activating protein 36*ENSMUSG0000003619813
Gm42906ENSMUSG000001070111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 biological_processGO:2000145 regulation of cell motility IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0005096 GTPase activator activity ISO
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000194 hypercalcemia "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

 MP:0001257 increased body length "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Ap4e1tm1a(KOMP)Wtsi/Ap4e1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Ap4e1tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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