ENSMUSG00000019874


Mus musculus

Features
Gene ID: ENSMUSG00000019874
  
Biological name :Fabp7
  
Synonyms : Fabp7 / Fatty acid-binding protein, brain / P51880
  
Possible biological names infered from orthology : fatty acid binding protein 7 / O15540
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B4
Gene start: 57784881
Gene end: 57788450
  
Corresponding Affymetrix probe sets: 10363224 (MoGene1.0st)   1450779_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000131415
Ensembl peptide - ENSMUSP00000020024
NCBI entrez gene - 12140     See in Manteia.
MGI - MGI:101916
RefSeq - NM_021272
RefSeq Peptide - NP_067247
swissprot - E9Q0H6
swissprot - P51880
Ensembl - ENSMUSG00000019874
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fabp7aENSDARG00000007697Danio rerio
 fabp7bENSDARG00000034650Danio rerio
 FABP7ENSGALG00000038933Gallus gallus
 FABP7ENSG00000164434Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fabp3 / P11404 / Fatty acid-binding protein, heart / P05413* / fatty acid binding protein 3*ENSMUSG0000002877365
Pmp2 / P24526 / peripheral myelin protein 2 / P02689*ENSMUSG0000005246855
Fabp4 / P04117 / Fatty acid-binding protein, adipocyte / P15090* / fatty acid binding protein 4*ENSMUSG0000006251553
Fabp12 / Q9DAK4 / Fatty acid-binding protein 12 / A6NFH5*ENSMUSG0000002753049
Fabp9 / O08716 / Fatty acid-binding protein 9 / Q0Z7S8*ENSMUSG0000002752846
Fabp5 / Q05816 / Fatty acid-binding protein, epidermal / Q01469* / fatty acid binding protein 5*ENSMUSG0000002753340
Crabp2 / P22935 / Cellular retinoic acid-binding protein 2 / P29373*ENSMUSG0000000488539
Crabp1 / P62965 / Cellular retinoic acid-binding protein 1 / P29762*ENSMUSG0000003229138
Rbp1 / Q00915 / retinol binding protein 1, cellular / P09455* / retinol binding protein 1*ENSMUSG0000004640237
Rbp7 / Q9EPC5 / retinol binding protein 7, cellular / Q96R05* / retinol binding protein 7*ENSMUSG0000002899636
Rbp2 / Q08652 / retinol binding protein 2, cellular / P50120* / retinol binding protein 2*ENSMUSG0000003245434
Gm37389 / FABP9* / Q0Z7S8* / fatty acid binding protein 9*ENSMUSG0000010312430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001964 startle response IMP
 biological_processGO:0021846 cell proliferation in forebrain IMP
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0050673 epithelial cell proliferation IEA
 biological_processGO:0060134 prepulse inhibition IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0042995 cell projection IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0044297 cell body IDA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0005504 fatty acid binding TAS
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0000812 abnormal dentate gyrus morphology "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0001902 reduced NMDA -mediated synaptic currents "reduction in the measured amplitude or duration of response to stimulation of NMDA receptors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0003638 abnormal response/metabolism to endogenous compounds "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0005282 decreased fatty acid level "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0008911 induced hyperactivity "increased physical activity following stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0009453 enhanced contextual conditioning "increase in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/cJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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