ENSMUSG00000020248


Mus musculus

Features
Gene ID: ENSMUSG00000020248
  
Biological name :Nfyb
  
Synonyms : Nfyb / Nuclear transcription factor Y subunit beta / P63139
  
Possible biological names infered from orthology : P25208
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 82748701
Gene end: 82764144
  
Corresponding Affymetrix probe sets: 10371307 (MoGene1.0st)   1419266_at (Mouse Genome 430 2.0 Array)   1419267_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116039
Ensembl peptide - ENSMUSP00000122403
NCBI entrez gene - 18045     See in Manteia.
MGI - MGI:97317
RefSeq - XM_011243381
RefSeq - NM_010914
RefSeq - XM_011243379
RefSeq - XM_011243380
RefSeq Peptide - NP_035044
swissprot - D3Z723
swissprot - P63139
Ensembl - ENSMUSG00000020248
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfybaENSDARG00000039185Danio rerio
 nfybbENSDARG00000045611Danio rerio
 NFYBENSGALG00000041193Gallus gallus
 NFYBENSG00000120837Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pole3 / polymerase (DNA directed), epsilon 3 (p17 subunit) / Q9NRF9* / DNA polymerase epsilon 3, accessory subunit*ENSMUSG0000002839420


Protein motifs (from Interpro)
Interpro ID Name
 IPR003956  Transcription factor, NFYB/HAP3, conserved site
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IC
 cellular_componentGO:0016602 CCAAT-binding factor complex IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032897 Nfyc / P70353 / Mus musculus nuclear transcription factor-Y gamma (Nfyc), transcript variant 4, mRNA. / Q13952* / nuclear transcription factor Y subunit gamma*  / complex
 ENSMUSG00000023994 Nfya / P23708 / Mus musculus nuclear transcription factor-Y alpha (Nfya), transcript variant 3, mRNA. / P23511* / nuclear transcription factor Y subunit alpha*  / complex
 ENSMUSG00000020538 Q9WTN3 / Srebf1 / Mus musculus sterol regulatory element binding transcription factor 1 (Srebf1), transcript variant 4, mRNA. / P36956* / sterol regulatory element binding transcription factor 1*  / complex / reaction






 

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