MP:0000440 | domed skull | |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0000787 | abnormal telencephalon morphology | "any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0001004 | abnormal photoreceptor morphology | "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0001891 | hydroencephaly | "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0002200 | abnormal brain ventricle/choroid plexus morphology | "malformation or absence of the brain ventricles or their associated choroid plexuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0002626 | increased heart rate | "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0002842 | increased blood pressure | "increased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0003731 | abnormal outer nuclear layer morphology | "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0004183 | abnormal sympathetic nervous system physiology | "anomaly in the function of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body s response to stressful situations" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0005458 | increased percent body fat | "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0006069 | abnormal retinal neuronal layer morphology | "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0006254 | thin cerebral cortex | "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0008283 | small hippocampus | "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0008545 | absent sperm flagella | "mature spermatozoa lack a flagella" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0008581 | disorganized photoreceptor inner segment | "derangement of the pattern of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pclotm3.3Sud/Pclotm3.3Sud Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0008583 | absent photoreceptor inner segment | "absence of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0008585 | absent photoreceptor outer segment | "absence of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0011056 | abnormal brain ependyma motile cilium morphology | "any structural anomaly of the tiny, motile hair-like projections from the epithelial cells that line the ventricles in the brain, which beat in concert and to move cerebrospinal fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0011069 | abnormal brain ependyma motile cilium physiology | "any functional anomaly of the tiny, motile hair-like projections from the epithelial cells that line the ventricles in the brain, which beat in concert and to move cerebrospinal fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0012468 | decreased striatum area | "reduced size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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MP:0030029 | wide cranial sutures | "an abnormally increased width of one or more cranial sutures for age-related norms, generally resulting from delayed suture closure" [HP:0010537] |
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Allelic Composition: Igf2tm4.1Wrk/Igf2+ Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SD7
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