ENSMUSG00000024076


Mus musculus

Features
Gene ID: ENSMUSG00000024076
  
Biological name :Vit
  
Synonyms : Q8VHI5 / Vit / vitrin
  
Possible biological names infered from orthology : Q6UXI7
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: E3
Gene start: 78508063
Gene end: 78627409
  
Corresponding Affymetrix probe sets: 10447006 (MoGene1.0st)   1426231_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024880
NCBI entrez gene - 74199     See in Manteia.
MGI - MGI:1921449
RefSeq - XM_006525029
RefSeq - NM_001197028
RefSeq - NM_028813
RefSeq - XM_006525028
RefSeq Peptide - NP_001183957
RefSeq Peptide - NP_083089
swissprot - Q8VHI5
Ensembl - ENSMUSG00000024076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ch1073-291c23.1ENSDARG00000063631Danio rerio
 VITENSGALG00000010583Gallus gallus
 VITENSG00000205221Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Coch / Q62507 / Cochlin / O43405*ENSMUSG0000002095336
A2AX52 / Col6a4 / Collagen alpha-4(VI) chain ENSMUSG0000003257224
Col6a5 / collagen type VI alpha 5 chain / A8TX70*ENSMUSG0000009134524
Col6a6 / Q8C6K9 / Collagen alpha-6(VI) chain / A6NMZ7* / collagen type VI alpha 6 chain*ENSMUSG0000004371923
Col6a3 / collagen, type VI, alpha 3 / P12111* / collagen type VI alpha 3 chain*ENSMUSG0000004812620
Q80X19 / Col14a1 / Collagen alpha-1(XIV) chain / Q05707* / collagen type XIV alpha 1 chain*ENSMUSG0000002237117
Q60847 / Col12a1 / Collagen alpha-1(XII) chain / Q99715* / collagen type XII alpha 1 chain*ENSMUSG0000003233217
Col7a1 / Q63870 / Collagen alpha-1(VII) chain / Q02388* / collagen type VII alpha 1 chain*ENSMUSG0000002565013
Vwa2 / Q70UZ7 / von Willebrand factor A domain containing 2 / Q5GFL6*ENSMUSG000000250829
Q923P0 / Col20a1 / Collagen alpha-1(XX) chain / Q9P218* / collagen type XX alpha 1 chain*ENSMUSG000000163566


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR004043  LCCL domain
 IPR030763  Vitrin
 IPR036465  von Willebrand factor A-like domain superfamily
 IPR036609  LCCL domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IDA
 biological_processGO:0030198 extracellular matrix organization IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005614 interstitial matrix IDA
 molecular_functionGO:0005539 glycosaminoglycan binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0000956 reduced spinal cord size "smaller appearance of the spinal cord" [J:35802]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0004100 abnormal spinal cord interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0004981 decreased neuronal precursor cell number "reduced number of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0009688 abnormal spinal cord central canal morphology "any structural anomaly of the ependyma-lined lumen of the spinal cord that is filled with cerebrospinal fluid; it is patent with the ventricular system of the brain and frequently becomes occluded in aging adults" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0010151 abnormal spinal cord ependymal layer morphology "any structural anomaly of the cellular membrane that lines the central canal of the spinal cord" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

 MP:0012203 abnormal neuronal stem cell morphology "any structural anomaly of an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors" [CL:0000047]
Show

Allelic Composition: Sf3b1tm1.1Mdf/Sf3b1+,Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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