ENSMUSG00000024485


Mus musculus
anionSlc4a9transporttransportermembraneactivitysodiuminorganictransmembraneintegralcomponenteukaryoticcotransporterc-terminalbandcytoplasmicdomainphosphotransferaseionregulationintracellularphplasmaapicalpartcellexchangersymportertransportersdigestive

Features
Gene ID: ENSMUSG00000024485
  
Biological name :Slc4a9
  
Synonyms : anion exchange protein 4 isoform 5 / Slc4a9
  
Possible biological names infered from orthology : Q96Q91 / solute carrier family 4 member 9
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B2
Gene start: 36528157
Gene end: 36541293
  
Corresponding Affymetrix probe sets: 10454885 (MoGene1.0st)   1439137_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073910
Ensembl peptide - ENSMUSP00000111358
NCBI entrez gene - 240215     See in Manteia.
MGI - MGI:2443384
RefSeq - NM_001271547
RefSeq - NM_172830
RefSeq - XM_017317896
RefSeq - NM_001271544
RefSeq - NM_001271545
RefSeq - NM_001271546
RefSeq - XM_006525907
RefSeq - XM_006525908
RefSeq - XM_006525909
RefSeq - XM_006525910
RefSeq - XM_006525911
RefSeq - XM_011246919
RefSeq - XM_011246920
RefSeq - XM_006525906
RefSeq Peptide - NP_001258473
RefSeq Peptide - NP_001258474
RefSeq Peptide - NP_001258475
RefSeq Peptide - NP_001258476
RefSeq Peptide - NP_766418
swissprot - Q8BUG8
swissprot - E9PUP3
Ensembl - ENSMUSG00000024485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC4A9ENSGALG00000044387Gallus gallus
 Q96Q91ENSG00000113073Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O88343 / Slc4a4 / solute carrier family 4 (anion exchanger), member 4 / Q9Y6R1* / solute carrier family 4 member 4*ENSMUSG0000006096149
Slc4a5 / solute carrier family 4 member 5 / Q9BY07*ENSMUSG0000006832345
Q8JZR6 / Slc4a8 / solute carrier family 4 (anion exchanger), member 8 / Q2Y0W8* / solute carrier family 4 member 8*ENSMUSG0000002303244
Slc4a7 / solute carrier family 4, sodium bicarbonate cotransporter, member 7 / Q9Y6M7* / solute carrier family 4 member 7*ENSMUSG0000002173343
Q5DTL9 / Slc4a10 / solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 / Q6U841* / solute carrier family 4 member 10*ENSMUSG0000002690443
P16283 / Slc4a3 / solute carrier family 4 (anion exchanger), member 3 / P48751* / solute carrier family 4 member 3*ENSMUSG0000000657636
Slc4a2 / solute carrier family 4 (anion exchanger), member 2 / P04920* / solute carrier family 4 member 2*ENSMUSG0000002896236
P04919 / Slc4a1 / solute carrier family 4 (anion exchanger), member 1 / P02730* / solute carrier family 4 member 1 (Diego blood group)*ENSMUSG0000000657432
A2AJN7 / Slc4a11 / Sodium bicarbonate transporter-like protein 11 / Q8NBS3* / solute carrier family 4 member 11*ENSMUSG0000007479621


Protein motifs (from Interpro)
Interpro ID Name
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR003024  Sodium bicarbonate cotransporter
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter


Gene Ontology (GO)
establishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationregulation of biological qualityestablishment of localizationestablishment of localizationregulation of biological qualityregulation of biological quality
transmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045177 apical part of cell ISS
 molecular_functionGO:0005452 inorganic anion exchanger activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity IBA


Pathways (from Reactome)
Pathway description
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
digestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotyperenal/urinary system phenotypedigestive/alimentary phenotypedigestive/alimentary phenotyperenal/urinary system phenotyperenal/urinary system phenotype
IDPhenotypeDefinition Genetic BG
 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trpc3Mwk/Trpc3+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0010107 abnormal renal reabsorption "any anomaly in the two-step process beginning with the active or passive extraction of substances (such as water, glucose, oligopeptides, amino acids, sodium (Na+) and other ions) from the renal tubule fluid into the renal interstitium, and the subsequent transport of these substances out of the renal interstitium back into the bloodstream; reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kdm6atm1c(EUCOMM)Wtsi/Kdm6atm1c(EUCOMM)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: either: (involves: C57BL/6 * CBA * CD-1) or (involves: 129 * C57BL/6 * CBA * CD-1)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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