ENSMUSG00000025144


Mus musculus
dnaCenpxkinetochorechromosomecentromerecellfanconicomplexbindingproteinxresolutionmeioticrecombinationintermediatesrepaircellularresponsedamagestimuluscyclereplicationforkprocessingdivisionassemblycentromericregioncondensednucleusanaemia

Features
Gene ID: ENSMUSG00000025144
  
Biological name :Cenpx
  
Synonyms : Cenpx / Mus musculus centromere protein X (Cenpx), transcript variant 3, mRNA. / Q8C4X1
  
Possible biological names infered from orthology : A8MT69 / centromere protein X
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 120710942
Gene end: 120713738
  
Corresponding Affymetrix probe sets: 10393917 (MoGene1.0st)   1416553_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101761
Ensembl peptide - ENSMUSP00000026137
Ensembl peptide - ENSMUSP00000050335
Ensembl peptide - ENSMUSP00000101760
NCBI entrez gene - 20892     See in Manteia.
MGI - MGI:894324
RefSeq - XM_017314405
RefSeq - XM_006532729
RefSeq - XM_011248848
RefSeq - XM_011248849
RefSeq - XM_011248851
RefSeq - XM_011248852
RefSeq - XM_011248853
RefSeq - NM_001347612
RefSeq - NM_016665
RefSeq - XM_006532728
RefSeq Peptide - NP_001334540
RefSeq Peptide - NP_001334541
RefSeq Peptide - NP_057874
swissprot - A2AC10
swissprot - Q8C4X1
swissprot - A2AC07
Ensembl - ENSMUSG00000025144
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenpxENSDARG00000089291Danio rerio
 CENPXENSGALG00000043607Gallus gallus
 CENPXENSG00000169689Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018552  Centromere protein X


Gene Ontology (GO)
nitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen compound metabolic processcellular component organizationcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclechromosome segregationresponse to stresscellular response to stimulusbiosynthetic processcell divisioncellular component biogenesisnitrogen conitrogen compound metabolic processcellular cocellular component organizationcellular mecellular metabolic processprimary metprimary metabolic processorganic suborganic substance metabolic processcell cyclecell cyclechromosome chromosome segregationresponse toresponse to stresscellular recellular response to stimulusbiosynthetibiosynthetic processcell divisicell divisioncellular cocellular component biogenesis
organic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound binding
cellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellcellorganelleorganelleprotein-containing complexprotein-containing complexmembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates ISS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031297 replication fork processing IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051382 kinetochore assembly IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0043240 Fanconi anaemia nuclear complex IBA
 cellular_componentGO:0071821 FANCM-MHF complex IBA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003690 double-stranded DNA binding ISS


Pathways (from Reactome)
Pathway description
Deposition of new CENPA-containing nucleosomes at the centromere
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025144 Cenpx / Q8C4X1 / Mus musculus centromere protein X (Cenpx), transcript variant 3, mRNA. / A8MT69* / centromere protein X*  / complex
 ENSMUSG00000030493 Faap24 / Q8BHL6 / Fanconi anemia core complex-associated protein 24 / Q9BTP7*  / complex
 ENSMUSG00000055884 Fancm / Q8BGE5 / Fanconi anemia group M protein homolog / Q8IYD8* / Fanconi anemia complementation group M*  / complex
 ENSMUSG00000073705 Cenps / Q9D084 / Centromere protein S / Q8N2Z9*  / complex






 

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