ENSMUSG00000025328


Mus musculus

Features
Gene ID: ENSMUSG00000025328
  
Biological name :Padi3
  
Synonyms : Padi3 / Protein-arginine deiminase type-3 / Q9Z184
  
Possible biological names infered from orthology : peptidyl arginine deiminase 3 / Q9ULW8
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 140785365
Gene end: 140810648
  
Corresponding Affymetrix probe sets: 10517808 (MoGene1.0st)   1419767_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130721
Ensembl peptide - ENSMUSP00000026377
NCBI entrez gene - 18601     See in Manteia.
MGI - MGI:1338891
RefSeq - NM_011060
RefSeq Peptide - NP_035190
swissprot - E9QAM4
swissprot - Q9Z184
Ensembl - ENSMUSG00000025328
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PADI3ENSG00000142619Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Padi1 / Q9Z185 / Protein-arginine deiminase type-1 / Q9ULC6* / peptidyl arginine deiminase 1*ENSMUSG0000002532957
Padi4 / Q9Z183 / Protein-arginine deiminase type-4 / Q9UM07* / peptidyl arginine deiminase 4*ENSMUSG0000002533053
Padi2 / Q08642 / Protein-arginine deiminase type-2 / Q9Y2J8* / peptidyl arginine deiminase 2*ENSMUSG0000002892751
Padi6 / Q8K3V4 / Protein-arginine deiminase type-6 / Q6TGC4* / peptidyl arginine deiminase 6*ENSMUSG0000004093543


Protein motifs (from Interpro)
Interpro ID Name
 IPR004303  Protein-arginine deiminase
 IPR008972  Cupredoxin
 IPR013530  Protein-arginine deiminase, C-terminal
 IPR013732  Protein-arginine deiminase (PAD) N-terminal
 IPR013733  Protein-arginine deiminase (PAD), central domain
 IPR036556  Protein-arginine deiminase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018101 protein citrullination IEA
 biological_processGO:0036414 histone citrullination IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004668 protein-arginine deiminase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Chromatin modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ube2j1tm1.1(NCOM)Mfgc/Ube2j1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Ube2j1tm1.1(NCOM)Mfgc/Rbrc

 MP:0002098 abnormal vibrissae morphology "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ube2j1tm1.1(NCOM)Mfgc/Ube2j1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Ube2j1tm1.1(NCOM)Mfgc/Rbrc

 MP:0002832 coarse hair "hair shafts that are twisted or coiled and are of uneven thickness produce an overall rugged or uneven appearance and roughness to the touch" [llw2:Linda Washburn , Mouse Genome Informatics Curator, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:56826]
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Allelic Composition: Ube2j1tm1.1(NCOM)Mfgc/Ube2j1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Ube2j1tm1.1(NCOM)Mfgc/Rbrc

 MP:0003809 abnormal hair shaft morphology "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Ube2j1tm1.1(NCOM)Mfgc/Ube2j1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Ube2j1tm1.1(NCOM)Mfgc/Rbrc

 MP:0010179 rough coat "coat does not have the usual smooth appearance" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ube2j1tm1.1(NCOM)Mfgc/Ube2j1tm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Ube2j1tm1.1(NCOM)Mfgc/Rbrc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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