ENSMUSG00000040935


Mus musculus

Features
Gene ID: ENSMUSG00000040935
  
Biological name :Padi6
  
Synonyms : Padi6 / Protein-arginine deiminase type-6 / Q8K3V4
  
Possible biological names infered from orthology : peptidyl arginine deiminase 6 / Q6TGC4
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 140727355
Gene end: 140742643
  
Corresponding Affymetrix probe sets: 10517774 (MoGene1.0st)   1437084_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123490
Ensembl peptide - ENSMUSP00000044044
NCBI entrez gene - 242726     See in Manteia.
MGI - MGI:2655198
RefSeq - NM_153106
RefSeq Peptide - NP_694746
swissprot - A2AMU1
swissprot - Q8K3V4
Ensembl - ENSMUSG00000040935
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PADI6ENSG00000276747Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Padi3 / Q9Z184 / Protein-arginine deiminase type-3 / Q9ULW8* / peptidyl arginine deiminase 3*ENSMUSG0000002532842
Padi1 / Q9Z185 / Protein-arginine deiminase type-1 / Q9ULC6* / peptidyl arginine deiminase 1*ENSMUSG0000002532941
Padi4 / Q9Z183 / Protein-arginine deiminase type-4 / Q9UM07* / peptidyl arginine deiminase 4*ENSMUSG0000002533040
Padi2 / Q08642 / Protein-arginine deiminase type-2 / Q9Y2J8* / peptidyl arginine deiminase 2*ENSMUSG0000002892739


Protein motifs (from Interpro)
Interpro ID Name
 IPR004303  Protein-arginine deiminase
 IPR008972  Cupredoxin
 IPR013530  Protein-arginine deiminase, C-terminal
 IPR013732  Protein-arginine deiminase (PAD) N-terminal
 IPR013733  Protein-arginine deiminase (PAD), central domain
 IPR036556  Protein-arginine deiminase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0007028 cytoplasm organization IMP
 biological_processGO:0018101 protein citrullination IEA
 biological_processGO:0034613 cellular protein localization IMP
 biological_processGO:0036414 histone citrullination IBA
 biological_processGO:0043143 regulation of translation by machinery localization IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 molecular_functionGO:0004668 protein-arginine deiminase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Chromatin modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001125 abnormal oocytes "anomalous structure of immature ova" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atp7aMo-2Btlr/Y
Genetic Background: C57BL/6J-Atp7aMo-2Btlr

Allelic Composition: Padi6tm1.1Jgo/Padi6tm1.1Jgo
Genetic Background: Not Specified

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atp7aMo-2Btlr/Y
Genetic Background: C57BL/6J-Atp7aMo-2Btlr

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Atp7aMo-2Btlr/Y
Genetic Background: C57BL/6J-Atp7aMo-2Btlr

Allelic Composition: Padi6tm1b(KOMP)Wtsi/Padi6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Padi6tm1b(KOMP)Wtsi/Ucd

 MP:0003406 failure of zygotic cell division "inability of a fertilized oocyte to initiate or complete early cell divisions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atp7aMo-2Btlr/Y
Genetic Background: C57BL/6J-Atp7aMo-2Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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