ENSMUSG00000027762


Mus musculus

Features
Gene ID: ENSMUSG00000027762
  
Biological name :Sucnr1
  
Synonyms : Q99MT6 / Succinate receptor 1 / Sucnr1
  
Possible biological names infered from orthology : Q9BXA5
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: D
Gene start: 60081869
Gene end: 60087566
  
Corresponding Affymetrix probe sets: 10492306 (MoGene1.0st)   1418804_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029326
NCBI entrez gene - 84112     See in Manteia.
MGI - MGI:1934135
RefSeq - NM_032400
RefSeq Peptide - NP_115776
swissprot - Q99MT6
Ensembl - ENSMUSG00000027762
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9BXA5ENSG00000198829Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2ry1 / P49650 / purinergic receptor P2Y, G-protein coupled 1 / P47900* / purinergic receptor P2Y1*ENSMUSG0000002776532
P2ry2 / purinergic receptor P2Y2 / P41231*ENSMUSG0000003286030
Oxgr1 / Q6IYF8 / 2-oxoglutarate receptor 1 / Q96P68* / oxoglutarate receptor 1*ENSMUSG0000004481929
P2ry6 / Q9ERK9 / P2Y purinoceptor 6 / Q15077* / pyrimidinergic receptor P2Y6*ENSMUSG0000004877928
Q920A1 / Cysltr2 / Cysteinyl leukotriene receptor 2 / Q9NS75*ENSMUSG0000003347026
P2ry4 / Q9JJS7 / P2Y purinoceptor 4 / P51582* / pyrimidinergic receptor P2Y4*ENSMUSG0000004435926
Gpr183 / Q3U6B2 / G protein-coupled receptor 183 / P32249*ENSMUSG0000005121226
Lpar6 / Q8BMC0 / Lysophosphatidic acid receptor 6 / P43657*ENSMUSG0000003344625
Lpar4 / Q8BLG2 / Lysophosphatidic acid receptor 4 / Q99677*ENSMUSG0000004992925
P2ry10 / Q8BFU7 / Mus musculus purinergic receptor P2Y, G-protein coupled 10 (P2ry10), transcript variant 2, mRNA. / O00398* / P2Y receptor family member 10*ENSMUSG0000005092125
Gpr17 / Q6NS65 / Uracil nucleotide/cysteinyl leukotriene receptor / Q13304* / G protein-coupled receptor 17*ENSMUSG0000005222925
Q99JA4 / Cysltr1 / Cysteinyl leukotriene receptor 1 / Q9Y271*ENSMUSG0000005282124
P2ry10b / purinergic receptor P2Y, G-protein coupled 10BENSMUSG0000005429323
Lpar5 / lysophosphatidic acid receptor 5 / Q9H1C0*ENSMUSG0000006771422
Ptafr / Q62035 / Platelet-activating factor receptor / P25105*ENSMUSG0000005652921
Gpr174 / Q3U507 / G protein-coupled receptor 174 / Q9BXC1*ENSMUSG0000007300821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001828 abnormal T cell activation "anomaly in the process of producing effector T cells from naive T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

 MP:0002136 abnormal kidney physiology "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Igh-Jtm1Jkbv/Igh-Jtm1Jkbv,Igkctm1Jkbv/Igkctm1Jkbv,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv
Genetic Background: involves: 129P2/OlaHsd

 MP:0002376 abnormal dendritic cell physiology "failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:85808]
Show

Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

 MP:0003353 decreased circulating renin level "reduced blood concentration of this enzyme which is secreted by the kidney; it cleaves a bond in angiotensionogen to generate angiotensin I " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Igh-Jtm1Jkbv/Igh-Jtm1Jkbv,Igkctm1Jkbv/Igkctm1Jkbv,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv
Genetic Background: involves: 129P2/OlaHsd

 MP:0004751 increased length of allograft survival "compared to controls, a greater length of time that transplanted tissue, in which the donor and recipient are genetically similar (same species) but not genetically identical, retains function and/or remains alive" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

 MP:0005362 abnormal Langerhans cell physiology "atypical or failure of normal function of the phagocytic dendritic cells principally found in the epidemis" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

 MP:0008686 abnormal interleukin-2 secretion "anomaly in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes" [MESH:D12.644.276.374.465.502]
Show

Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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