ENSMUSG00000067714


Mus musculus

Features
Gene ID: ENSMUSG00000067714
  
Biological name :Lpar5
  
Synonyms : Lpar5 / lysophosphatidic acid receptor 5
  
Possible biological names infered from orthology : Q9H1C0
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F2
Gene start: 125067920
Gene end: 125082472
  
Corresponding Affymetrix probe sets: 10541799 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000085630
Ensembl peptide - ENSMUSP00000119904
Ensembl peptide - ENSMUSP00000132511
NCBI entrez gene - 381810     See in Manteia.
MGI - MGI:2685918
RefSeq - NM_001163269
RefSeq - NM_001163268
RefSeq - XM_006506340
RefSeq Peptide - NP_001156740
RefSeq Peptide - NP_001156741
swissprot - G3X9K0
swissprot - F6S365
Ensembl - ENSMUSG00000067714
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpar5aENSDARG00000010384Danio rerio
 LPAR5ENSGALG00000014455Gallus gallus
 LPAR5ENSG00000184574Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lpar6 / Q8BMC0 / Lysophosphatidic acid receptor 6 / P43657*ENSMUSG0000003344630
Lpar4 / Q8BLG2 / Lysophosphatidic acid receptor 4 / Q99677*ENSMUSG0000004992929
P2ry4 / Q9JJS7 / P2Y purinoceptor 4 / P51582* / pyrimidinergic receptor P2Y4*ENSMUSG0000004435927
P2ry2 / purinergic receptor P2Y2 / P41231*ENSMUSG0000003286024
P2ry6 / Q9ERK9 / P2Y purinoceptor 6 / Q15077* / pyrimidinergic receptor P2Y6*ENSMUSG0000004877924
Gpr17 / Q6NS65 / Uracil nucleotide/cysteinyl leukotriene receptor / Q13304* / G protein-coupled receptor 17*ENSMUSG0000005222924
Gpr174 / Q3U507 / G protein-coupled receptor 174 / Q9BXC1*ENSMUSG0000007300824
Gpr183 / Q3U6B2 / G protein-coupled receptor 183 / P32249*ENSMUSG0000005121223
P2ry1 / P49650 / purinergic receptor P2Y, G-protein coupled 1 / P47900* / purinergic receptor P2Y1*ENSMUSG0000002776522
Q920A1 / Cysltr2 / Cysteinyl leukotriene receptor 2 / Q9NS75*ENSMUSG0000003347022
P2ry10 / Q8BFU7 / Mus musculus purinergic receptor P2Y, G-protein coupled 10 (P2ry10), transcript variant 2, mRNA. / O00398* / P2Y receptor family member 10*ENSMUSG0000005092122
Q99JA4 / Cysltr1 / Cysteinyl leukotriene receptor 1 / Q9Y271*ENSMUSG0000005282122
P2ry10b / purinergic receptor P2Y, G-protein coupled 10BENSMUSG0000005429322
Oxgr1 / Q6IYF8 / 2-oxoglutarate receptor 1 / Q96P68* / oxoglutarate receptor 1*ENSMUSG0000004481921
Ptafr / Q62035 / Platelet-activating factor receptor / P25105*ENSMUSG0000005652921
Q99MT6 / Sucnr1 / Succinate receptor 1 / Q9BXA5*ENSMUSG0000002776218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001360 abnormal social investigation "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0001970 abnormal pain threshold "increased or decreased average level of perception of pain" [J:17792]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0002062 abnormal conditioning behavior "inability to change the frequency or form of a behavior as a result of the influence of the environment " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0002574 increased vertical activity "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0002736 abnormal nociception after inflammation "changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0003858 enhanced coordination "improved ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

 MP:0005498 hyporesponsive to tactile stimuli "reduced reflex action normally induced by touch or pain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Agpat2Gt(OST438470)Lex/Agpat2Gt(OST438470)Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0012306 enhanced spatial learning "enhanced ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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