ENSMUSG00000044819


Mus musculus

Features
Gene ID: ENSMUSG00000044819
  
Biological name :Oxgr1
  
Synonyms : 2-oxoglutarate receptor 1 / Oxgr1 / Q6IYF8
  
Possible biological names infered from orthology : oxoglutarate receptor 1 / Q96P68
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: E4
Gene start: 120019585
Gene end: 120042435
  
Corresponding Affymetrix probe sets: 10422387 (MoGene1.0st)   1456989_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055137
NCBI entrez gene - 239283     See in Manteia.
MGI - MGI:2685145
RefSeq - NM_001001490
RefSeq Peptide - NP_001001490
swissprot - Q6IYF8
Ensembl - ENSMUSG00000044819
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oxgr1a.1ENSDARG00000033684Danio rerio
 oxgr1a.2ENSDARG00000078743Danio rerio
 oxgr1a.3ENSDARG00000040247Danio rerio
 oxgr1bENSDARG00000029803Danio rerio
 ENSGALG00000016891Gallus gallus
 ENSGALG00000041311Gallus gallus
 OXGR1ENSG00000165621Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2ry1 / P49650 / purinergic receptor P2Y, G-protein coupled 1 / P47900* / purinergic receptor P2Y1*ENSMUSG0000002776533
P2ry6 / Q9ERK9 / P2Y purinoceptor 6 / Q15077* / pyrimidinergic receptor P2Y6*ENSMUSG0000004877931
P2ry2 / purinergic receptor P2Y2 / P41231*ENSMUSG0000003286030
P2ry4 / Q9JJS7 / P2Y purinoceptor 4 / P51582* / pyrimidinergic receptor P2Y4*ENSMUSG0000004435929
Q920A1 / Cysltr2 / Cysteinyl leukotriene receptor 2 / Q9NS75*ENSMUSG0000003347028
Q99MT6 / Sucnr1 / Succinate receptor 1 / Q9BXA5*ENSMUSG0000002776227
Gpr17 / Q6NS65 / Uracil nucleotide/cysteinyl leukotriene receptor / Q13304* / G protein-coupled receptor 17*ENSMUSG0000005222926
Q99JA4 / Cysltr1 / Cysteinyl leukotriene receptor 1 / Q9Y271*ENSMUSG0000005282126
Lpar6 / Q8BMC0 / Lysophosphatidic acid receptor 6 / P43657*ENSMUSG0000003344625
Lpar4 / Q8BLG2 / Lysophosphatidic acid receptor 4 / Q99677*ENSMUSG0000004992925
Lpar5 / lysophosphatidic acid receptor 5 / Q9H1C0*ENSMUSG0000006771424
P2ry10b / purinergic receptor P2Y, G-protein coupled 10BENSMUSG0000005429323
Gpr174 / Q3U507 / G protein-coupled receptor 174 / Q9BXC1*ENSMUSG0000007300823
Gpr183 / Q3U6B2 / G protein-coupled receptor 183 / P32249*ENSMUSG0000005121221
P2ry10 / Q8BFU7 / Mus musculus purinergic receptor P2Y, G-protein coupled 10 (P2ry10), transcript variant 2, mRNA. / O00398* / P2Y receptor family member 10*ENSMUSG0000005092120
Ptafr / Q62035 / Platelet-activating factor receptor / P25105*ENSMUSG0000005652919


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001973 adenosine receptor signaling pathway IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001609 G-protein coupled adenosine receptor activity ISO
 molecular_functionGO:0001883 purine nucleoside binding ISO
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016208 AMP binding ISO


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001790 abnormal immune system physiology "deviation from the normal function of the immune system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ubr4tm1.2Nkt/Ubr4tm1.2Nkt,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL

Allelic Composition: Cysltr1tm1Ykn/Cysltr1tm1Ykn,Cysltr2tm1Ykn/Cysltr2tm1Ykn,Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6NTac

 MP:0003016 increased circulating bicarbonate level "elevated concentration of inorganic salts that contain the -HCO3 radical in the circulation, which are an important factor in regulating the pH of the blood " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Ndfip1tm1.1Pmo/Ndfip1tm1.1Pmo,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Ndfip1tm1.1Pmo/Ndfip1tm1.1Pmo,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0009350 decreased urine pH "increased urine acidity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Ndfip1tm1.1Pmo/Ndfip1tm1.1Pmo,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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