ENSMUSG00000028089


Mus musculus

Features
Gene ID: ENSMUSG00000028089
  
Biological name :Chd1l
  
Synonyms : Chd1l / Chromodomain-helicase-DNA-binding protein 1-like / Q9CXF7
  
Possible biological names infered from orthology : Q86WJ1
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 97560742
Gene end: 97610203
  
Corresponding Affymetrix probe sets: 10500445 (MoGene1.0st)   1449415_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029730
NCBI entrez gene - 68058     See in Manteia.
MGI - MGI:1915308
RefSeq - XM_017319701
RefSeq - NM_026539
RefSeq - XM_017319699
RefSeq - XM_017319700
RefSeq Peptide - NP_080815
swissprot - Q9CXF7
Ensembl - ENSMUSG00000028089
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chd1lENSDARG00000015471Danio rerio
 CHD1LENSGALG00000015038Gallus gallus
 CHD1LENSG00000131778Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PGB8 / Smarca1 / Mus musculus SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (Smarca1), transcript variant 3, mRNA. / P28370* / SWI/SNF ...ENSMUSG0000003109932
Q91ZW3 / Smarca5 / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 / O60264*ENSMUSG0000003171531


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR002589  Macro domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031053  Chromodomain-helicase-DNA-binding protein 1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006338 chromatin remodeling ISS
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding ISO
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031446 Cul4a / Q3TCH7 / Cullin-4A / Q13619*  / complex / reaction
 ENSMUSG00000031095 Cul4b / A2A432 / Cullin-4B / Q13620*  / complex / reaction
 ENSMUSG00000024740 Ddb1 / Q3U1J4 / DNA damage-binding protein 1 / Q16531* / damage specific DNA binding protein 1*  / complex / reaction
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / complex / reaction
 ENSMUSG00000026496 Parp1 / poly (ADP-ribose) polymerase family, member 1 / P09874* / poly(ADP-ribose) polymerase 1*  / complex / reaction
 ENSMUSG00000002109 Ddb2 / Q99J79 / DNA damage-binding protein 2 / Q92466* / damage specific DNA binding protein 2*  / complex / reaction
 ENSMUSG00000028329 Xpa / Q64267 / xeroderma pigmentosum, complementation group A / P23025* / XPA, DNA damage recognition and repair factor*  / complex / reaction
 ENSMUSG00000028426 P54728 / Rad23b / UV excision repair B / P54727* / RAD23 homolog B, nucleotide excision repair protein*  / complex / reaction
 ENSMUSG00000031347 Cetn2 / Q9R1K9 / Centrin-2 / P41208*  / complex / reaction
 ENSMUSG00000030094 Xpc / P51612 / xeroderma pigmentosum, complementation group C / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / complex / reaction






 

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