ENSMUSG00000028330


Mus musculus

Features
Gene ID: ENSMUSG00000028330
  
Biological name :Ncbp1
  
Synonyms : Ncbp1 / Nuclear cap-binding protein subunit 1 / Q3UYV9
  
Possible biological names infered from orthology : Q09161
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B1
Gene start: 46138613
Gene end: 46172403
  
Corresponding Affymetrix probe sets: 10504703 (MoGene1.0st)   1433663_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030014
NCBI entrez gene - 433702     See in Manteia.
MGI - MGI:1891840
RefSeq - NM_001033201
RefSeq - XM_017320296
RefSeq Peptide - NP_001028373
swissprot - Q3UYV9
Ensembl - ENSMUSG00000028330
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NCBP1ENSGALG00000002087Gallus gallus
 NCBP1ENSG00000136937Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003890  MIF4G-like, type 3
 IPR015172  MIF4G-like, type 1
 IPR015174  MIF4G-like, type 2
 IPR016024  Armadillo-type fold
 IPR027159  Nuclear cap-binding protein subunit 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISS
 biological_processGO:0000245 spliceosomal complex assembly IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0006370 7-methylguanosine mRNA capping ISO
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016070 RNA metabolic process IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031053 primary miRNA processing IBA
 biological_processGO:0031442 positive regulation of mRNA 3"-end processing IEA
 biological_processGO:0045292 mRNA cis splicing, via spliceosome IEA
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IEA
 biological_processGO:1905216 positive regulation of RNA binding IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005845 mRNA cap binding complex IEA
 cellular_componentGO:0005846 nuclear cap binding complex IBA
 cellular_componentGO:0034518 RNA cap binding complex IEA
 molecular_functionGO:0000339 RNA cap binding IBA
 molecular_functionGO:0000340 RNA 7-methylguanosine cap binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
SLBP independent Processing of Histone Pre-mRNAs
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transport of Mature mRNA derived from an Intron-Containing Transcript
snRNP Assembly
RNA Polymerase II Pre-transcription Events
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3-end processing
Processing of Capped Intron-Containing Pre-mRNA
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Processing of Intronless Pre-mRNAs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003435 Supt5 / O55201 / Transcription elongation factor SPT5 / O00267* / SUPT5H* / SPT5 homolog, DSIF elongation factor subunit*  / complex / reaction
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / complex / reaction
 ENSMUSG00000060475 Wtap / Q9ER69 / Wilms tumour 1-associating protein / Q15007* / WT1 associated protein*  / reaction
 ENSMUSG00000008301 Phax / Q9JJT9 / phosphorylated adaptor for RNA export / Q9H814*  / complex / reaction
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / complex / reaction
 ENSMUSG00000031256 Cstf2 / Q8BIQ5 / Cleavage stimulation factor subunit 2 / P33240*  / reaction / complex
 ENSMUSG00000033323 Ctdp1 / Q7TSG2 / RNA polymerase II subunit A C-terminal domain phosphatase / Q9Y5B0* / CTD phosphatase subunit 1*  / complex / reaction
 ENSMUSG00000046434 P49312 / Hnrnpa1 / Heteroous nuclear ribonucleoprotein A1 Heteroous nuclear ribonucleoprotein A1, N-terminally processed / P09651* / heterogeneous nuclear ribonucleoprotein A1*  / complex / reaction
 ENSMUSG00000027176 Cstf3 / Q99LI7 / Cleavage stimulation factor subunit 3 / Q12996*  / complex / reaction
 ENSMUSG00000053536 Cstf2t / Q8C7E9 / Cleavage stimulation factor subunit 2 tau variant / Q9H0L4*  / complex / reaction
 ENSMUSG00000027498 Cstf1 / Q99LC2 / Cleavage stimulation factor subunit 1 / Q05048*  / complex / reaction
 ENSMUSG00000029111 Nelfa / Q8BG30 / Negative elongation factor A / Q9H3P2* / negative elongation factor complex member A*  / complex / reaction
 ENSMUSG00000037364 Srrt / Q99MR6 / Serrate RNA effector molecule homolog / Q9BXP5* / serrate, RNA effector molecule*  / complex / reaction
 ENSMUSG00000028114 Q3UIK4 / Mettl14 / N6-adenosine-methyltransferase non-catalytic subunit / Q9HCE5* / methyltransferase like 14*  / reaction
 ENSMUSG00000004642 Slbp / P97440 / stem-loop binding protein / Q14493*  / complex / reaction
 ENSMUSG00000041815 Q8BG81 / Poldip3 / Mus musculus polymerase (DNA-directed), delta interacting protein 3 (Poldip3), transcript variant 2, mRNA. / Q9BY77* / DNA polymerase delta interacting protein 3*  / complex
 ENSMUSG00000048012 Q8BI67 / Zfp473 / zinc finger protein 473 / Q8WTR7* / ZNF473*  / complex / reaction
 ENSMUSG00000045983 Eif4g1 / Q6NZJ6 / Eukaryotic translation initiation factor 4 gamma 1 / Q04637*  / complex
 ENSMUSG00000051732 Pabpc2 / P11940* / PABPC1* / poly(A) binding protein cytoplasmic 1*  / complex
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / complex / reaction
 ENSMUSG00000020485 P63271 / Supt4a / suppressor of Ty 4A / P63272* / SUPT4H1* / SPT4 homolog, DSIF elongation factor subunit*  / complex / reaction
 ENSMUSG00000024369 Nelfe / P19426 / negative elongation factor complex member E, Rdbp / P18615* / negative elongation factor complex member E*  / complex / reaction






 

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