ENSMUSG00000051732


Mus musculus

Features
Gene ID: ENSMUSG00000051732
  
Biological name :Pabpc2
  
Synonyms : Pabpc2
  
Possible biological names infered from orthology : P11940 / PABPC1 / poly(A) binding protein cytoplasmic 1
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B3
Gene start: 39773497
Gene end: 39776082
  
Corresponding Affymetrix probe sets: 10455289 (MoGene1.0st)   1419500_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066639
NCBI entrez gene - 18459     See in Manteia.
MGI - MGI:1349723
RefSeq - NM_011033
RefSeq Peptide - NP_035163
swissprot - Q62029
Ensembl - ENSMUSG00000051732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pabpc1aENSDARG00000017219Danio rerio
 pabpc1bENSDARG00000021140Danio rerio
 P11940ENSG00000070756Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P29341 / Pabpc1 / Polyadenylate-binding protein 1 ENSMUSG0000002228381
Pabpc6ENSMUSG0000004617371
Pabpc4 / poly(A) binding protein, cytoplasmic 4 / Q13310*ENSMUSG0000001125768
Pabpc1l / poly(A) binding protein, cytoplasmic 1-like / Q4VXU2*ENSMUSG0000005458255
Pabpc4l / poly(A) binding protein cytoplasmic 4 like / P0CB38*ENSMUSG0000009091937
Pabpc5 / poly(A) binding protein cytoplasmic 5 / Q96DU9*ENSMUSG0000003473236
Rbms1 / Q91W59 / RNA-binding motif, single-stranded-interacting protein 1 / P29558*ENSMUSG0000002697016
Rbms3 / Q8BWL5 / RNA binding motif, single stranded interacting protein / Q6XE24* / RNA binding motif single stranded interacting protein 3*ENSMUSG0000003960715
Rbms2 / Q8VC70 / RNA-binding motif, single-stranded-interacting protein 2 / Q15434*ENSMUSG0000004004315
Puf60 / Q3UEB3 / Poly(U)-binding-splicing factor PUF60 / Q9UHX1* / poly(U) binding splicing factor 60*ENSMUSG0000000252413
Elavl3 / Q60900 / ELAV-like protein 3 / Q14576* / ELAV like RNA binding protein 3*ENSMUSG0000000341012
Elavl2 / Q60899 / Mus musculus ELAV like RNA binding protein 1 (Elavl2), transcript variant 5, mRNA. / Q12926* / ELAV like RNA binding protein 2*ENSMUSG0000000848912
Elavl4 / Q61701 / Mus musculus ELAV like RNA binding protein 4 (Elavl4), transcript variant 5, mRNA. / P26378* / ELAV like RNA binding protein 4*ENSMUSG0000002854612
Elavl1 / P70372 / ELAV-like protein 1 / Q15717* / ELAV like RNA binding protein 1*ENSMUSG0000004002811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002004  Polyadenylate-binding protein/Hyperplastic disc protein
 IPR003954  RNA recognition motif domain, eukaryote
 IPR006515  Polyadenylate binding protein, human types 1, 2, 3, 4
 IPR035979  RNA-binding domain superfamily
 IPR036053  PABC (PABP) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008143 poly(A) binding ISS


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
AUF1 (hnRNP D0) binds and destabilizes mRNA
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000045983 Eif4g1 / Q6NZJ6 / Eukaryotic translation initiation factor 4 gamma 1 / Q04637*  / complex
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / complex
 ENSMUSG00000028330 Ncbp1 / Q3UYV9 / Nuclear cap-binding protein subunit 1 / Q09161*  / complex






 

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