ENSMUSG00000031111


Mus musculus

Features
Gene ID: ENSMUSG00000031111
  
Biological name :Igsf1
  
Synonyms : Igsf1 / Immunoglobulin superfamily member 1 / Q7TQA1
  
Possible biological names infered from orthology : Q8N6C5
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 49782536
Gene end: 49797749
  
Corresponding Affymetrix probe sets: 10604473 (MoGene1.0st)   1433652_at (Mouse Genome 430 2.0 Array)   1438589_at (Mouse Genome 430 2.0 Array)   1447702_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033442
Ensembl peptide - ENSMUSP00000071919
Ensembl peptide - ENSMUSP00000110541
Ensembl peptide - ENSMUSP00000110543
NCBI entrez gene - 209268     See in Manteia.
MGI - MGI:2147913
RefSeq - XM_011251004
RefSeq - NM_177591
RefSeq - NM_177915
RefSeq - NM_183335
RefSeq - NM_183336
RefSeq - XM_006541482
RefSeq - XM_006541484
RefSeq - XM_006541487
RefSeq - XM_011251002
RefSeq - XM_011251003
RefSeq Peptide - NP_808583
RefSeq Peptide - NP_899178
RefSeq Peptide - NP_899179
RefSeq Peptide - NP_808259
swissprot - Q7TQA1
Ensembl - ENSMUSG00000031111
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IGSF1L3ENSGALG00000030005Gallus gallus
 IGSF1ENSG00000147255Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1bg / Q19LI2 / alpha-1-B glycoprotein / P04217*ENSMUSG000000223479
Tarm1 / B6A8R8 / T-cell-interacting, activating receptor on myeloid cells protein 1 / B6A8C7* / T cell-interacting, activating receptor on myeloid cells 1*ENSMUSG000000533385
Oscar / Q8VBT3 / Osteoclast-associated immunoglobulin-like receptor / Q8IYS5*ENSMUSG000000545945


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0007165 signal transduction ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0034711 inhibin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000633 abnormal pituitary gland morphology "anomalous structure of the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0003503 decreased activity of thyroid 
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0005119 decreased circulating thyroid-stimulating hormone level "less than expected blood concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0005134 decreased thyroid-stimulating hormone level "less than expected concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0005479 decreased circulating triiodothyronine level "less than the normal blood concentration of this hormone synthesized and secreted by the thyroid; normally, this is the main thyroid hormone used by the tissues " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Skiltm2Spw/Skiltm2Spw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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