ENSMUSG00000031957


Mus musculus

Features
Gene ID: ENSMUSG00000031957
  
Biological name :Ctrb1
  
Synonyms : Chymotrypsinogen B Chymotrypsin B chain A Chymotrypsin B chain B Chymotrypsin B chain C / Ctrb1 / Q9CR35
  
Possible biological names infered from orthology : chymotrypsinogen B1 / chymotrypsinogen B2 / CTRB2 / P17538 / Q6GPI1
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: E1
Gene start: 111686519
Gene end: 111691010
  
Corresponding Affymetrix probe sets: 10581882 (MoGene1.0st)   1448220_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034435
NCBI entrez gene - 66473     See in Manteia.
MGI - MGI:88559
RefSeq - NM_025583
RefSeq Peptide - NP_079859
swissprot - Q9CR35
Ensembl - ENSMUSG00000031957
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctrb1ENSDARG00000090428Danio rerio
 zgc:112160ENSDARG00000039730Danio rerio
 zgc:136461ENSDARG00000093844Danio rerio
 ENSGALG00000046107Gallus gallus
 CTRB2ENSGALG00000000038Gallus gallus
 CTRB1ENSG00000168925Homo sapiens
 CTRB2ENSG00000168928Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctrl / chymotrypsin-like / P40313*ENSMUSG0000003189655
Cela3b / Q9CQ52 / Chymotrypsin-like elastase family member 3B / P08861* / P09093* / CELA3A* / chymotrypsin like elastase family member 3A*ENSMUSG0000002343343
Cela3a / chymotrypsin-like elastase family, member 3A / P09093* / CELA3B* / P08861* / chymotrypsin like elastase family member 3B*ENSMUSG0000007852040
Cela2a / P05208 / Chymotrypsin-like elastase family member 2A / CELA2B* / P08218* / P08217* / chymotrypsin like elastase family member 2B*ENSMUSG0000005857939
Ovch2 / Q7M761 / Ovochymase-2 / ovochymase 2 (gene/pseudogene)*ENSMUSG0000004823638
Ctrc / chymotrypsin-C / Q99895*ENSMUSG0000006247838
Cela1 / Q91X79 / Chymotrypsin-like elastase family member 1 / Q9UNI1*ENSMUSG0000002303137


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0007586 digestion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031957 Ctrb1 / Q9CR35 / Chymotrypsinogen B Chymotrypsin B chain A Chymotrypsin B chain B Chymotrypsin B chain C / CTRB2* / P17538* / Q6GPI1* / chymotrypsinogen B1* / chymotrypsinogen B2*  / complex






 

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