ENSMUSG00000032374


Mus musculus

Features
Gene ID: ENSMUSG00000032374
  
Biological name :Plod2
  
Synonyms : Plod2 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 / Q9R0B9
  
Possible biological names infered from orthology : O00469
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 92542223
Gene end: 92608428
  
Corresponding Affymetrix probe sets: 10587829 (MoGene1.0st)   1416686_at (Mouse Genome 430 2.0 Array)   1416687_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068611
Ensembl peptide - ENSMUSP00000125373
NCBI entrez gene - 26432     See in Manteia.
MGI - MGI:1347007
RefSeq - NM_001142916
RefSeq - NM_011961
RefSeq Peptide - NP_001136388
RefSeq Peptide - NP_036091
swissprot - Q9R0B9
swissprot - E9Q718
Ensembl - ENSMUSG00000032374
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plod2ENSDARG00000011821Danio rerio
 PLOD2ENSGALG00000006783Gallus gallus
 PLOD2ENSG00000152952Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plod3 / Q9R0E1 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 / O60568*ENSMUSG0000000484656
Plod1 / Q9R0E2 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 / Q02809*ENSMUSG0000001905556
Q6NVG7 / Colgalt2 / Procollagen galactosyltransferase 2 / Q8IYK4* / collagen beta(1-O)galactosyltransferase 2*ENSMUSG0000003264915
Q8K297 / Colgalt1 / Procollagen galactosyltransferase 1 / Q8NBJ5* / collagen beta(1-O)galactosyltransferase 1*ENSMUSG0000003480713
A3KGW5 / Cercam / Inactive glycosyltransferase 25 family member 3 / Q5T4B2* / cerebral endothelial cell adhesion molecule*ENSMUSG0000003978713


Protein motifs (from Interpro)
Interpro ID Name
 IPR001006  Procollagen-lysine 5-dioxygenase
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0017185 peptidyl-lysine hydroxylation IEA
 biological_processGO:0046947 hydroxylysine biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030867 rough endoplasmic reticulum membrane IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008475 procollagen-lysine 5-dioxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000004846 Plod3 / Q9R0E1 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 / O60568*  / reaction
 ENSMUSG00000019055 Plod1 / Q9R0E2 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 / Q02809*  / reaction
 ENSMUSG00000032374 Plod2 / Q9R0B9 / Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 / O00469*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr