ENSMUSG00000035337


Mus musculus

Features
Gene ID: ENSMUSG00000035337
  
Biological name :Uchl4
  
Synonyms : P58321 / ubiquitin carboxyl-terminal esterase L4 / Uchl4
  
Possible biological names infered from orthology : P15374 / ubiquitin C-terminal hydrolase L3 / UCHL3
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: C
Gene start: 64235201
Gene end: 64236362
  
Corresponding Affymetrix probe sets: 10586180 (MoGene1.0st)   1421766_at (Mouse Genome 430 2.0 Array)   1449855_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045208
NCBI entrez gene - 93841     See in Manteia.
MGI - MGI:1890440
RefSeq - NM_033607
RefSeq Peptide - NP_291085
swissprot - B2RTM4
swissprot - P58321
Ensembl - ENSMUSG00000035337
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uchl3ENSDARG00000030177Danio rerio
 UCHL3ENSGALG00000016921Gallus gallus
 UCHL3ENSG00000118939Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Uchl3 / Q9JKB1 / ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) / P15374* / ubiquitin C-terminal hydrolase L3*ENSMUSG0000002211195
Uchl1 / Q9R0P9 / ubiquitin carboxy-terminal hydrolase L1 / P09936* / ubiquitin C-terminal hydrolase L1*ENSMUSG0000002922351


Protein motifs (from Interpro)
Interpro ID Name
 IPR001578  Peptidase C12, ubiquitin carboxyl-terminal hydrolase
 IPR036959  Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
UCH proteinases
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000010376 Nedd8 / P29595 / Q15843* / neural precursor cell expressed, developmentally down-regulated 8*  / complex
 ENSMUSG00000068240 P62984 / Gm11808 / predicted gene 11808 / UBA52* / P62987* / ubiquitin A-52 residue ribosomal protein fusion product 1*  / reaction
 ENSMUSG00000020460 P62983 / Rps27a / ribosomal protein S27A / P62979*  / reaction






 

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