Manteia

ENSMUSG00000036295

Mus musculus

Features

Gene ID:	ENSMUSG00000036295

Biological name :	Lrrn3

Synonyms :	Leucine-rich repeat neuronal protein 3 / Lrrn3 / Q8CBC6

Possible biological names infered from orthology :	leucine rich repeat neuronal 3 / Q9H3W5

Species:	Mus musculus

Chr. number:	12
Strand:	-1
Band:	B1
Gene start:	41451668
Gene end:	41486431

Corresponding Affymetrix probe sets:	10400126 (MoGene1.0st) 1434539_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000043818 NCBI entrez gene - 16981 See in Manteia. MGI - MGI:106036 RefSeq - NM_010733 RefSeq - NM_001271708 RefSeq - NM_001271709 RefSeq Peptide - NP_001258637 RefSeq Peptide - NP_001258638 RefSeq Peptide - NP_034863 swissprot - Q8CBC6 Ensembl - ENSMUSG00000036295

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
lrrn3a	ENSDARG00000077569	Danio rerio
lrrn3b	ENSDARG00000102702	Danio rerio
LRRN3	ENSGALG00000009488	Gallus gallus
LRRN3	ENSG00000173114	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Lrrn1 / Q61809 / Leucine-rich repeat neuronal protein 1 / Q6UXK5* / leucine rich repeat neuronal 1*	ENSMUSG00000034648	52
Lrrn2 / leucine rich repeat protein 2, neuronal / O75325* / leucine rich repeat neuronal 2*	ENSMUSG00000026443	46
Lingo2 / Q3URE9 / leucine rich repeat and Ig domain containing 2 / Q7L985*	ENSMUSG00000045083	23
Lingo1 / Q9D1T0 / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 / Q96FE5* / leucine rich repeat and Ig domain containing 1*	ENSMUSG00000049556	21
Lingo3 / Q6GQU6 / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 / P0C6S8* / leucine rich repeat and Ig domain containing 3*	ENSMUSG00000051067	21
Lrfn5 / Q8BXA0 / Leucine-rich repeat and fibronectin type-III domain-containing protein 5 / Q96NI6* / leucine rich repeat and fibronectin type III domain containing 5*	ENSMUSG00000035653	20
Lrfn2 / Q80TG9 / Leucine-rich repeat and fibronectin type-III domain-containing protein 2 / Q9ULH4* / leucine rich repeat and fibronectin type III domain containing 2*	ENSMUSG00000040490	20
Lingo4 / leucine rich repeat and Ig domain containing 4 / Q6UY18*	ENSMUSG00000044505	20
Lrrc4b / P0C192 / Leucine-rich repeat-containing protein 4B / Q9NT99* / leucine rich repeat containing 4B*	ENSMUSG00000047085	20
Lrrc4 / Q99PH1 / Leucine-rich repeat-containing protein 4 / Q9HBW1* / leucine rich repeat containing 4*	ENSMUSG00000049939	20
Lrrc4c / Q8C031 / Leucine-rich repeat-containing protein 4C / Q9HCJ2* / leucine rich repeat containing 4C*	ENSMUSG00000050587	20
Lrfn3 / Q8BLY3 / Leucine-rich repeat and fibronectin type-III domain-containing protein 3 / Q9BTN0* / leucine rich repeat and fibronectin type III domain containing 3*	ENSMUSG00000036957	19
Lrfn4 / Q80XU8 / Leucine-rich repeat and fibronectin type-III domain-containing protein 4 / Q6PJG9* / leucine rich repeat and fibronectin type III domain containing 4*	ENSMUSG00000045045	19
Lrfn1 / Q2WF71 / Leucine-rich repeat and fibronectin type III domain-containing protein 1 / Q9P244* / leucine rich repeat and fibronectin type III domain containing 1*	ENSMUSG00000030600	18

Protein motifs (from Interpro)

Interpro ID	Name
IPR000372	Leucine-rich repeat N-terminal domain
IPR000483	Cysteine-rich flanking region, C-terminal
IPR001611	Leucine-rich repeat
IPR003591	Leucine-rich repeat, typical subtype
IPR003598	Immunoglobulin subtype 2
IPR003599	Immunoglobulin subtype
IPR003961	Fibronectin type III
IPR007110	Immunoglobulin-like domain
IPR013098	Immunoglobulin I-set
IPR013783	Immunoglobulin-like fold
IPR032675	Leucine-rich repeat domain superfamily
IPR036116	Fibronectin type III superfamily
IPR036179	Immunoglobulin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0051965	positive regulation of synapse assembly	IDA
cellular_component	GO:0005615	extracellular space	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005515	protein binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0005292	improved glucose tolerance	"better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Hspg2^tm1Soni/Hspg2^tm1Soni Genetic Background: involves: 129S/SvEv * DBA/2J
MP:0005458	increased percent body fat	"more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Hspg2^tm1Soni/Hspg2^tm1Soni Genetic Background: involves: 129S/SvEv * DBA/2J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr