ENSMUSG00000037797


Mus musculus

Features
Gene ID: ENSMUSG00000037797
  
Biological name :Adh4
  
Synonyms : Adh4 / Alcohol dehydrogenase 4 / Q9QYY9
  
Possible biological names infered from orthology : alcohol dehydrogenase 4 (class II), pi polypeptide / P08319
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G3
Gene start: 138415466
Gene end: 138430892
  
Corresponding Affymetrix probe sets: 10496466 (MoGene1.0st)   1422070_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124163
Ensembl peptide - ENSMUSP00000013458
NCBI entrez gene - 26876     See in Manteia.
MGI - MGI:1349472
RefSeq - NM_011996
RefSeq Peptide - NP_036126
swissprot - E0CYI4
swissprot - Q9QYY9
Ensembl - ENSMUSG00000037797
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adh5ENSDARG00000080010Danio rerio
 adh8aENSDARG00000091211Danio rerio
 adh8bENSDARG00000024278Danio rerio
 zgc:63568ENSDARG00000087262Danio rerio
 zgc:77938ENSDARG00000088366Danio rerio
 ADH4ENSG00000198099Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adh5 / P28474 / Alcohol dehydrogenase class-3 / P11766* / alcohol dehydrogenase 5 (class III), chi polypeptide*ENSMUSG0000002813855
Adh1 / P00329 / Alcohol dehydrogenase 1 / ADH1C* / ADH1A* / ADH1B* / P07327* / P00325* / P00326* / alcohol dehydrogenase 1B (class I), beta polypeptide* / alcohol dehydrogenase 1A (class I...ENSMUSG0000007420754
Adh7 / Q64437 / Alcohol dehydrogenase class 4 mu/sigma chain / P40394* / alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide*ENSMUSG0000005530152
Adh6a / alcohol dehydrogenase 6A (class V) / ADH6* / P28332* / alcohol dehydrogenase 6 (class V)*ENSMUSG0000005305447
Adh6b / alcohol dehydrogenase 6B (class V) / ADH6* / P28332* / alcohol dehydrogenase 6 (class V)*ENSMUSG0000007420629


Protein motifs (from Interpro)
Interpro ID Name
 IPR002328  Alcohol dehydrogenase, zinc-type, conserved site
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR028632  Alcohol dehydrogenase family, zinc-type, class-II subfamily
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process IEA
 biological_processGO:0006066 alcohol metabolic process IEA
 biological_processGO:0006067 ethanol metabolic process IDA
 biological_processGO:0006069 ethanol oxidation ISO
 biological_processGO:0006081 cellular aldehyde metabolic process IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0046164 alcohol catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1901661 quinone metabolic process IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003960 NADPH:quinone reductase activity IDA
 molecular_functionGO:0004022 alcohol dehydrogenase (NAD) activity ISO
 molecular_functionGO:0004024 alcohol dehydrogenase activity, zinc-dependent ISO
 molecular_functionGO:0004032 alditol:NADP+ 1-oxidoreductase activity IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity IEA
 molecular_functionGO:0005503 all-trans retinal binding IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0019115 benzaldehyde dehydrogenase activity IEA
 molecular_functionGO:0019841 retinol binding IEA
 molecular_functionGO:0035276 ethanol binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037797 Adh4 / Q9QYY9 / Alcohol dehydrogenase 4 / P08319* / alcohol dehydrogenase 4 (class II), pi polypeptide*  / complex






 

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