ENSMUSG00000038244


Mus musculus

Features
Gene ID: ENSMUSG00000038244
  
Biological name :Mical2
  
Synonyms : [F-actin]-monooxygenase MICAL2 / Mical2 / Q8BML1
  
Possible biological names infered from orthology : microtubule associated monooxygenase, calponin and LIM domain containing 2 / O94851 / Q6ZW33
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F1
Gene start: 112225856
Gene end: 112355194
  
Corresponding Affymetrix probe sets: 10556381 (MoGene1.0st)   1438726_at (Mouse Genome 430 2.0 Array)   1455685_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047639
Ensembl peptide - ENSMUSP00000051163
Ensembl peptide - ENSMUSP00000123341
NCBI entrez gene - 320878     See in Manteia.
MGI - MGI:2444947
RefSeq - XM_006507954
RefSeq - NM_001193305
RefSeq - NM_177282
RefSeq Peptide - NP_001180234
RefSeq Peptide - NP_796256
swissprot - Q8BML1
swissprot - F6WY65
Ensembl - ENSMUSG00000038244
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1RA39ENSDARG00000020395Danio rerio
 mical2aENSDARG00000075608Danio rerio
 MICAL2ENSGALG00000005540Gallus gallus
 MICAL2ENSG00000133816Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mical3 / Q8CJ19 / [F-actin]-monooxygenase MICAL3 / Q7RTP6* / microtubule associated monooxygenase, calponin and LIM domain containing 3*ENSMUSG0000005158651
Mical1 / Q8VDP3 / Mus musculus microtubule associated monooxygenase, calponin and LIM domain containing 1 (Mical1), transcript variant 4, mRNA. / Q8TDZ2* / microtubule associated monooxygen...ENSMUSG0000001982334
Ehbp1l1 / EH domain-binding protein 1-like protein 1 isoform C / Q8N3D4* / EH domain binding protein 1 like 1*ENSMUSG0000002493711
Q5SXY1 / Specc1 / sperm antigen with calponin homology and coiled-coil domains 1 / Q5M775*ENSMUSG0000004233110
Q9D5U9 / Micalcl / MICAL C-terminal-like protein ENSMUSG000000307719
Q2KN98 / Specc1l / sperm antigen with calponin homology and coiled-coil domains 1-like / Q69YQ0* / SPECC1L-ADORA2A* / SPECC1L-ADORA2A readthrough (NMD candidate)*ENSMUSG000000334449
Ehbp1 / Q69ZW3 / EH domain-binding protein 1 / Q8NDI1*ENSMUSG000000423029
AC132392.1ENSMUSG000001111879
Smtn / Q921U8 / Smoothelin / P53814*ENSMUSG000000204398
Q8BGT6 / Micall1 / MICAL-like protein 1 / Q8N3F8* / MICAL like 1*ENSMUSG000000330398
Q3TN34 / Micall2 / MICAL-like protein 2 / Q8IY33* / MICAL like 2*ENSMUSG000000367188
Q8CI12 / Smtnl2 / Smoothelin-like protein 2 / Q2TAL5* / smoothelin like 2*ENSMUSG000000456676
Q99LM3 / Smtnl1 / Smoothelin-like protein 1 / A8MU46* / smoothelin like 1*ENSMUSG000000270775


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR001781  Zinc finger, LIM-type
 IPR002938  FAD-binding domain
 IPR029939  MICAL2
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping ISS
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0010735 positive regulation of transcription via serum response element binding IEA
 biological_processGO:0019417 sulfur oxidation IDA
 biological_processGO:0030042 actin filament depolymerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ISS
 molecular_functionGO:0043914 NADPH:sulfur oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071949 FAD binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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