ENSMUSG00000019823


Mus musculus

Features
Gene ID: ENSMUSG00000019823
  
Biological name :Mical1
  
Synonyms : Mical1 / Mus musculus microtubule associated monooxygenase, calponin and LIM domain containing 1 (Mical1), transcript variant 4, mRNA. / Q8VDP3
  
Possible biological names infered from orthology : microtubule associated monooxygenase, calponin and LIM domain containing 1 / Q8TDZ2
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B2
Gene start: 41476314
Gene end: 41487032
  
Corresponding Affymetrix probe sets: 10362767 (MoGene1.0st)   1416759_at (Mouse Genome 430 2.0 Array)   1456439_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019967
Ensembl peptide - ENSMUSP00000113783
Ensembl peptide - ENSMUSP00000114969
Ensembl peptide - ENSMUSP00000116386
Ensembl peptide - ENSMUSP00000097519
NCBI entrez gene - 171580     See in Manteia.
MGI - MGI:2385847
RefSeq - XM_017313820
RefSeq - NM_001164433
RefSeq - NM_001358839
RefSeq - NM_138315
RefSeq - XM_006512570
RefSeq - XM_006512574
RefSeq - XM_011243137
RefSeq Peptide - NP_612188
RefSeq Peptide - NP_001157905
RefSeq Peptide - NP_001345768
swissprot - E9PUI4
swissprot - Q8VDP3
swissprot - D3Z5P6
Ensembl - ENSMUSG00000019823
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E7F9T0ENSDARG00000011809Danio rerio
 MICAL1ENSGALG00000032190Gallus gallus
 MICAL1ENSG00000135596Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mical3 / Q8CJ19 / [F-actin]-monooxygenase MICAL3 / Q7RTP6* / microtubule associated monooxygenase, calponin and LIM domain containing 3*ENSMUSG0000005158645
Q8BML1 / Mical2 / [F-actin]-monooxygenase MICAL2 / O94851* / Q6ZW33* / microtubule associated monooxygenase, calponin and LIM domain containing 2*ENSMUSG0000003824435
Ehbp1l1 / EH domain-binding protein 1-like protein 1 isoform C / Q8N3D4* / EH domain binding protein 1 like 1*ENSMUSG0000002493715
Q9D5U9 / Micalcl / MICAL C-terminal-like protein ENSMUSG0000003077114
AC132392.1ENSMUSG0000011118714
Ehbp1 / Q69ZW3 / EH domain-binding protein 1 / Q8NDI1*ENSMUSG0000004230213
Q8BGT6 / Micall1 / MICAL-like protein 1 / Q8N3F8* / MICAL like 1*ENSMUSG0000003303912
Q3TN34 / Micall2 / MICAL-like protein 2 / Q8IY33* / MICAL like 2*ENSMUSG0000003671812
Q5SXY1 / Specc1 / sperm antigen with calponin homology and coiled-coil domains 1 / Q5M775*ENSMUSG0000004233111
Q2KN98 / Specc1l / sperm antigen with calponin homology and coiled-coil domains 1-like / Q69YQ0* / SPECC1L-ADORA2A* / SPECC1L-ADORA2A readthrough (NMD candidate)*ENSMUSG0000003344410
Smtn / Q921U8 / Smoothelin / P53814*ENSMUSG000000204399
Q8CI12 / Smtnl2 / Smoothelin-like protein 2 / Q2TAL5* / smoothelin like 2*ENSMUSG000000456677
Q99LM3 / Smtnl1 / Smoothelin-like protein 1 / A8MU46* / smoothelin like 1*ENSMUSG000000270775


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR001781  Zinc finger, LIM-type
 IPR002938  FAD-binding domain
 IPR022735  bMERB domain
 IPR029937  MICAL1
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0019417 sulfur oxidation IDA
 biological_processGO:0030042 actin filament depolymerization IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0055114 oxidation-reduction process ISO
 biological_processGO:1903305 regulation of regulated secretory pathway IMP
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:1990026 hippocampal mossy fiber expansion IMP
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0004497 monooxygenase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071949 FAD binding ISO


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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