ENSMUSG00000038591


Mus musculus

Features
Gene ID: ENSMUSG00000038591
  
Biological name :Colec10
  
Synonyms : Colec10 / Collectin-10 / Q8CF98
  
Possible biological names infered from orthology : collectin subfamily member 10 / Q9Y6Z7
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D1
Gene start: 54410774
Gene end: 54466358
  
Corresponding Affymetrix probe sets: 10424105 (MoGene1.0st)   1457871_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037867
NCBI entrez gene - 239447     See in Manteia.
MGI - MGI:3606482
RefSeq - XM_011245616
RefSeq - NM_173422
RefSeq - XM_011245615
RefSeq Peptide - NP_775598
swissprot - Q8CF98
Ensembl - ENSMUSG00000038591
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COLEC10ENSDARG00000104752Danio rerio
 Q2LK95ENSGALG00000033144Gallus gallus
 Q9Y6Z7ENSG00000184374Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Colec11 / collectin subfamily member 11 / Q9BWP8*ENSMUSG0000003665545
Sftpd / P50404 / Pulmonary surfactant-associated protein D / P35247* / surfactant protein D*ENSMUSG0000002179528
Sftpa1 / surfactant associated protein A1 / SFTPA2* / Q8IWL1* / Q8IWL2* / surfactant protein A1* / surfactant protein A2*ENSMUSG0000002178926
Mbl1 / P39039 / Mannose-binding protein A ENSMUSG0000003778026
Mbl2 / P41317 / mannose-binding lectin (protein C) 2 / P11226* / mannose binding lectin 2*ENSMUSG0000002486323


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR008160  Collagen triple helix repeat
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033990  Collectin, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response NAS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules NAS
 biological_processGO:0009792 embryo development ending in birth or egg hatching NAS
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:1904888 cranial skeletal system development IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol NAS
 molecular_functionGO:0005537 mannose binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042056 chemoattractant activity IEA


Pathways (from Reactome)
Pathway description
Lectin pathway of complement activation
Initial triggering of complement


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036655 Colec11 / collectin subfamily member 11 / Q9BWP8*  / complex
 ENSMUSG00000024371 C2 / P21180 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681* / complement C2*  / reaction
 ENSMUSG00000073418 C4b / P01029 / Complement C4-B Complement C4 beta chain Complement C4 alpha chain C4a anaphylatoxin Complement C4 gamma chain / C4A* / P0C0L4* / P0C0L5* / complement C4B (Chido blood group)...  / reaction
 ENSMUSG00000028979 Masp2 / Q91WP0 / Mannan-binding lectin serine protease 2 Mannan-binding lectin serine protease 2 A chain Mannan-binding lectin serine protease 2 B chain / O00187* / mannan binding lectin se...  / complex
 ENSMUSG00000022887 Masp1 / P98064 / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant 1, mRNA. / P48740* / mannan binding lectin serine peptidase 1*  / complex






 

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