ENSMUSG00000040489


Mus musculus

Features
Gene ID: ENSMUSG00000040489
  
Biological name :Sox30
  
Synonyms : Q8CGW4 / Sox30 / Transcription factor SOX-30
  
Possible biological names infered from orthology : O94993 / SRY-box 30
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B1.1
Gene start: 45980310
Gene end: 46017994
  
Corresponding Affymetrix probe sets: 10375396 (MoGene1.0st)   1440509_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037519
NCBI entrez gene - 214105     See in Manteia.
MGI - MGI:1341157
RefSeq - NM_173384
RefSeq - XM_006532797
RefSeq Peptide - NP_775560
swissprot - Q8CGW4
Ensembl - ENSMUSG00000040489
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOX30ENSGALG00000045860Gallus gallus
 SOX30ENSG00000039600Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sox5 / P35710 / SRY (sex determining region Y)-box 5 / P35711* / SRY-box 5*ENSMUSG0000004154015
Sox6 / P40645 / SRY (sex determining region Y)-box 6 / P35712* / SRY-box 6*ENSMUSG0000005191015
Sox13 / Q04891 / Transcription factor SOX-13 / Q9UN79* / SRY-box 13*ENSMUSG0000007064314


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007283 spermatogenesis IEP
 biological_processGO:0031960 response to corticosteroid IEA
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

Allelic Composition: Sox30tm1a(KOMP)Wtsi/Sox30tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

Allelic Composition: Sox30tm1a(KOMP)Wtsi/Sox30tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox30tm1a(KOMP)Wtsi/Sox30tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0008279 arrest of spermiogenesis "block in the process by which a spermatid transforms into a functional spermatozoon" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

Allelic Composition: Sox30tm1a(KOMP)Wtsi/Sox30tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0020550 multinucleated giant male germ cells "presence of large cells containing multiple nuclei formed abnormal opening of the cytoplasmic bridges that are part of normal germ cell division" [PMID:16272280, url:https://ntp.niehs.nih.gov/nnl/male_reproductive/testis/setubmgcel/index.htm]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

Allelic Composition: Sox30tm1a(KOMP)Wtsi/Sox30tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr