ENSMUSG00000043531


Mus musculus

Features
Gene ID: ENSMUSG00000043531
  
Biological name :Sorcs1
  
Synonyms : Sorcs1 / sortilin related VPS10 domain containing receptor 1
  
Possible biological names infered from orthology : Q8WY21
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: D1
Gene start: 50143299
Gene end: 50678646
  
Corresponding Affymetrix probe sets: 10468452 (MoGene1.0st)   1421509_at (Mouse Genome 430 2.0 Array)   1425864_a_at (Mouse Genome 430 2.0 Array)   1436662_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000072472
Ensembl peptide - ENSMUSP00000148254
Ensembl peptide - ENSMUSP00000147591
Ensembl peptide - ENSMUSP00000147463
Ensembl peptide - ENSMUSP00000147456
Ensembl peptide - ENSMUSP00000132615
Ensembl peptide - ENSMUSP00000129190
Ensembl peptide - ENSMUSP00000107386
NCBI entrez gene - 58178     See in Manteia.
MGI - MGI:1929666
RefSeq - XM_017318265
RefSeq - NM_001252501
RefSeq - NM_001290356
RefSeq - NM_021377
RefSeq - XM_006527243
RefSeq - XM_006527244
RefSeq - XM_011247308
RefSeq Peptide - NP_067352
RefSeq Peptide - NP_001277285
RefSeq Peptide - NP_001239430
swissprot - E9PYT6
swissprot - A0A1B0GT94
swissprot - A0A1B0GRN1
swissprot - A0A1B0GRC4
swissprot - E9QQ02
swissprot - A0A1B0GRB7
swissprot - E9QQ63
swissprot - E9Q203
Ensembl - ENSMUSG00000043531
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017711.1ENSDARG00000112034Danio rerio
 SORCS1ENSGALG00000008465Gallus gallus
 Q8WY21ENSG00000108018Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8VI51 / Sorcs3 / VPS10 domain-containing receptor SorCS3 / Q9UPU3* / sortilin related VPS10 domain containing receptor 3*ENSMUSG0000006343462
Q9EPR5 / Sorcs2 / sortilin-related VPS10 domain containing receptor 2 / Q96PQ0*ENSMUSG0000002909341
Sorl1 / O88307 / Sortilin-related receptor / Q92673* / sortilin related receptor 1*ENSMUSG0000004931322
Sort1 / Q6PHU5 / Sortilin / Q99523* / sortilin 1*ENSMUSG0000006874716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR006581  VPS10
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003329 amyloid beta deposits 
Show

Allelic Composition: Sf1Gt(XD130)Byg/Sf1+
Genetic Background: involves: 129P2/OlaHsd * 129S1/SvImJ * MOLF/Ei

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr