ENSMUSG00000043531


Mus musculus

Features
Gene ID: ENSMUSG00000043531
  
Biological name :Sorcs1
  
Synonyms : Sorcs1 / sortilin related VPS10 domain containing receptor 1
  
Possible biological names infered from orthology : Q8WY21
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: D1
Gene start: 50143299
Gene end: 50678646
  
Corresponding Affymetrix probe sets: 10468452 (MoGene1.0st)   1421509_at (Mouse Genome 430 2.0 Array)   1425864_a_at (Mouse Genome 430 2.0 Array)   1436662_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000072472
Ensembl peptide - ENSMUSP00000148254
Ensembl peptide - ENSMUSP00000147591
Ensembl peptide - ENSMUSP00000147463
Ensembl peptide - ENSMUSP00000147456
Ensembl peptide - ENSMUSP00000132615
Ensembl peptide - ENSMUSP00000129190
Ensembl peptide - ENSMUSP00000107386
NCBI entrez gene - 58178     See in Manteia.
MGI - MGI:1929666
RefSeq - XM_017318265
RefSeq - NM_001252501
RefSeq - NM_001290356
RefSeq - NM_021377
RefSeq - XM_006527243
RefSeq - XM_006527244
RefSeq - XM_011247308
RefSeq Peptide - NP_067352
RefSeq Peptide - NP_001277285
RefSeq Peptide - NP_001239430
swissprot - E9PYT6
swissprot - A0A1B0GT94
swissprot - A0A1B0GRN1
swissprot - A0A1B0GRC4
swissprot - E9QQ02
swissprot - A0A1B0GRB7
swissprot - E9QQ63
swissprot - E9Q203
Ensembl - ENSMUSG00000043531
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017711.1ENSDARG00000112034Danio rerio
 SORCS1ENSGALG00000008465Gallus gallus
 Q8WY21ENSG00000108018Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8VI51 / Sorcs3 / VPS10 domain-containing receptor SorCS3 / Q9UPU3* / sortilin related VPS10 domain containing receptor 3*ENSMUSG0000006343462
Q9EPR5 / Sorcs2 / sortilin-related VPS10 domain containing receptor 2 / Q96PQ0*ENSMUSG0000002909341
Sorl1 / O88307 / Sortilin-related receptor / Q92673* / sortilin related receptor 1*ENSMUSG0000004931322
Sort1 / Q6PHU5 / Sortilin / Q99523* / sortilin 1*ENSMUSG0000006874716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR006581  VPS10
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003329 amyloid beta deposits 
Show

Allelic Composition: Sf1Gt(XD130)Byg/Sf1+
Genetic Background: involves: 129P2/OlaHsd * 129S1/SvImJ * MOLF/Ei

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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