ENSMUSG00000044749


Mus musculus

Features
Gene ID: ENSMUSG00000044749
  
Biological name :Abca6
  
Synonyms : Abca6 / ATP-binding cassette, sub-family A (ABC1), member 6 / Q8K441
  
Possible biological names infered from orthology : ATP binding cassette subfamily A member 6 / Q8N139
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 110176820
Gene end: 110251776
  
Corresponding Affymetrix probe sets: 10392601 (MoGene1.0st)   1453817_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035458
NCBI entrez gene - 76184     See in Manteia.
MGI - MGI:1923434
RefSeq - XM_006534414
RefSeq - NM_147218
RefSeq - XM_006534413
RefSeq Peptide - NP_671751
swissprot - Q8K441
Ensembl - ENSMUSG00000044749
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000021395Gallus gallus
 ENSGALG00000021399Gallus gallus
 ABCA6ENSG00000154262Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Abca9 / Q8K449 / ATP-binding cassette, sub-family A (ABC1), member 9 / Q8IUA7* / ATP binding cassette subfamily A member 9*ENSMUSG0000004179753
Q8K440 / Abca8b / ATP-binding cassette, sub-family A (ABC1), member 8b / ABCA8* / O94911* / ATP binding cassette subfamily A member 8*ENSMUSG0000002062052
Abca8a / Q8K442 / ATP-binding cassette, sub-family A (ABC1), member 8aENSMUSG0000004182850
Abca5 / Q8K448 / ATP-binding cassette, sub-family A (ABC1), member 5 / Q8WWZ7* / ATP binding cassette subfamily A member 5*ENSMUSG0000001880039
Abca1 / P41233 / ATP-binding cassette, sub-family A (ABC1), member 1 / O95477* / ATP binding cassette subfamily A member 1*ENSMUSG0000001524326
Abca7 / Q91V24 / ATP-binding cassette, sub-family A (ABC1), member 7 / Q8IZY2* / ATP binding cassette subfamily A member 7*ENSMUSG0000003572225
Abca13 / Q5SSE9 / ATP-binding cassette, sub-family A (ABC1), member 13 / Q86UQ4* / ATP binding cassette subfamily A member 13*ENSMUSG0000000466824
Abca2 / ATP-binding cassette, sub-family A (ABC1), member 2 / Q9BZC7* / ATP binding cassette subfamily A member 2*ENSMUSG0000002694424
Abca4 / O35600 / ATP-binding cassette, sub-family A (ABC1), member 4 / P78363* / ATP binding cassette subfamily A member 4*ENSMUSG0000002812524
Abca3 / Q8R420 / ATP-binding cassette, sub-family A (ABC1), member 3 / Q99758* / ATP binding cassette subfamily A member 3*ENSMUSG0000002413023
Abca12 / ATP-binding cassette, sub-family A (ABC1), member 12 / Q86UK0* / ATP binding cassette subfamily A member 12*ENSMUSG0000005029623
Abca15 / ATP-binding cassette, sub-family A (ABC1), member 15ENSMUSG0000005474623
Abca14 / ATP-binding cassette, sub-family A (ABC1), member 14ENSMUSG0000006201722
Abca17 / E9PX95 / ATP-binding cassette, sub-family A (ABC1), member 17ENSMUSG0000003543521
Abca16 / ATP-binding cassette, sub-family A (ABC1), member 16ENSMUSG0000005190021


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030368  ATP-binding cassette subfamily A member 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Abca1tm1b(EUCOMM)Hmgu/Abca1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Abca1tm1b(EUCOMM)Hmgu/Bay

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Abca1tm1b(EUCOMM)Hmgu/Abca1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Abca1tm1b(EUCOMM)Hmgu/Bay

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Abca1tm1b(EUCOMM)Hmgu/Abca1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Abca1tm1b(EUCOMM)Hmgu/Bay

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
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Allelic Composition: Abca1tm1b(EUCOMM)Hmgu/Abca1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Abca1tm1b(EUCOMM)Hmgu/Bay

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Abca1tm1b(EUCOMM)Hmgu/Abca1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Abca1tm1b(EUCOMM)Hmgu/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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