ENSMUSG00000045532


Mus musculus

Features
Gene ID: ENSMUSG00000045532
  
Biological name :C1ql1
  
Synonyms : C1ql1 / C1q-related factor / O88992
  
Possible biological names infered from orthology : complement C1q like 1 / O75973
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 102939264
Gene end: 102946688
  
Corresponding Affymetrix probe sets: 10391828 (MoGene1.0st)   1422777_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050469
NCBI entrez gene - 23829     See in Manteia.
MGI - MGI:1344400
RefSeq - NM_011795
RefSeq Peptide - NP_035925
swissprot - O88992
Ensembl - ENSMUSG00000045532
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c1ql3bENSDARG00000028521Danio rerio
 C1QL1ENSGALG00000028031Gallus gallus
 C1QL1ENSG00000131094Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C1ql3 / Q9ESN4 / Complement C1q-like protein 3 / Q5VWW1* / complement C1q like 3*ENSMUSG0000004963073
C1ql4 / Q4ZJM9 / Complement C1q-like protein 4 / Q86Z23* / complement C1q like 4*ENSMUSG0000000107667
C1ql2 / Q8CFR0 / Complement C1q-like protein 2 / Q7Z5L3* / complement C1q like 2*ENSMUSG0000003690767
Q05A80 / Caprin2 / Q6IMN6* / caprin family member 2*ENSMUSG0000003030927
Q9ES30 / C1qtnf3 / Complement C1q tumor necrosis factor-related protein 3 / Q9BXJ4* / C1QTNF3-AMACR* / C1q and TNF related 3* / C1QTNF3-AMACR readthrough (NMD candidate)*ENSMUSG0000005891422
Cbln2 / Q8BGU2 / Cerebellin-2 / Q8IUK8* / cerebellin 2 precursor*ENSMUSG0000002464721
Cbln3 / Q9JHG0 / Cerebellin-3 / Q6UW01* / cerebellin 3 precursor*ENSMUSG0000004038021
Cbln1 / Q9R171 / Cerebellin-1 Cerebellin [des-Ser1]-cerebellin / P23435* / cerebellin 1 precursor*ENSMUSG0000003165420
Cbln4 / Q8BME9 / Cerebellin-4 / Q9NTU7* / cerebellin 4 precursor*ENSMUSG0000006757819
Q60865 / Caprin1 / Q14444* / cell cycle associated protein 1*ENSMUSG0000002718415


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008160  Collagen triple helix repeat
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016322 neuron remodeling IMP
 biological_processGO:0061743 motor learning IGI
 biological_processGO:0099558 maintenance of synapse structure IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0043083 synaptic cleft IDA
 cellular_componentGO:0044301 climbing fiber IDA
 cellular_componentGO:0098793 presynapse IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001899 absent long term depression "lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc,Tg(Scn10a-cre)1Rkun/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2

 MP:0002804 abnormal motor learning "defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc,Tg(Scn10a-cre)1Rkun/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc,Tg(Scn10a-cre)1Rkun/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2

 MP:0003412 abnormal afterhyperpolarization "anomaly in the currents that follow an action potential and influence firing frequency and neuronal integration" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94941]
Show

Allelic Composition: Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc,Tg(Scn10a-cre)1Rkun/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2

 MP:0003463 abnormal single cell response "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc,Tg(Scn10a-cre)1Rkun/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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