ENSMUSG00000046794


Mus musculus

Features
Gene ID: ENSMUSG00000046794
  
Biological name :Ppp1r3b
  
Synonyms : Ppp1r3b / Protein phosphatase 1 regulatory subunit 3B / Q8C767
  
Possible biological names infered from orthology : Q86XI6
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A4
Gene start: 35375739
Gene end: 35388139
  
Corresponding Affymetrix probe sets: 10571321 (MoGene1.0st)   1436590_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065679
Ensembl peptide - ENSMUSP00000147633
Ensembl peptide - ENSMUSP00000147736
NCBI entrez gene - 244416     See in Manteia.
MGI - MGI:2177268
RefSeq - XM_017312798
RefSeq - NM_177741
RefSeq - XM_006509118
RefSeq - XM_017312797
RefSeq Peptide - NP_808409
swissprot - Q8C767
Ensembl - ENSMUSG00000046794
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q803M0ENSDARG00000044691Danio rerio
 PPP1R3BENSGALG00000030303Gallus gallus
 Q86XI6ENSG00000173281Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7TMB3 / Ppp1r3c / Protein phosphatase 1 regulatory subunit 3C / Q9UQK1*ENSMUSG0000006727942
Q99MR9 / Ppp1r3a / Protein phosphatase 1 regulatory subunit 3A / Q16821*ENSMUSG0000004271722
Ppp1r3d / protein phosphatase 1 regulatory subunit 3D / O95685*ENSMUSG0000004999921
Q9CW07 / Ppp1r3g / Protein phosphatase 1 regulatory subunit 3G / B7ZBB8*ENSMUSG0000005042321
Ppp1r3e / protein phosphatase 1, regulatory (inhibitor) subunit 3E / Q9H7J1* / protein phosphatase 1 regulatory subunit 3E*ENSMUSG0000007249420


Protein motifs (from Interpro)
Interpro ID Name
 IPR005036  CBM21 (carbohydrate binding type-21) domain
 IPR013783  Immunoglobulin-like fold
 IPR017434  Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa
 IPR030682  Protein phosphatase 1 regulatory subunit 3B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0005979 regulation of glycogen biosynthetic process IEA
 biological_processGO:0005981 regulation of glycogen catabolic process ISO
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000164 protein phosphatase type 1 complex IEA
 cellular_componentGO:0042587 glycogen granule IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

Allelic Composition: Ppp1r3btm1.1Arte/Ppp1r3b+
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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