ENSMUSG00000048528


Mus musculus

Features
Gene ID: ENSMUSG00000048528
  
Biological name :Nkx1-2
  
Synonyms : NK1 transcription factor-related protein 2 / Nkx1-2 / P42580
  
Possible biological names infered from orthology : NK1 homeobox 2 / Q9UD57
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 132594878
Gene end: 132599637
  
Corresponding Affymetrix probe sets: 10568581 (MoGene1.0st)   1422049_at (Mouse Genome 430 2.0 Array)   1422050_at (Mouse Genome 430 2.0 Array)   1426177_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052778
NCBI entrez gene - 20231     See in Manteia.
MGI - MGI:104806
RefSeq - NM_009123
RefSeq Peptide - NP_033149
swissprot - P42580
Ensembl - ENSMUSG00000048528
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx1.2laENSDARG00000006350Danio rerio
 NKX1-2ENSG00000229544Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nkx1-1 / NK1 transcription factor-related protein 1 / Q15270* / NK1 homeobox 1*ENSMUSG0000002911246
Mnx1 / Q9QZW9 / motor neuron and pancreas homeobox 1 / P50219*ENSMUSG0000000156623
Evx1 / P23683 / Homeobox even-skipped homolog protein 1 / P49640* / even-skipped homeobox 1*ENSMUSG0000000550320
Gbx2 / P48031 / Homeobox protein GBX-2 / P52951* / gastrulation brain homeobox 2*ENSMUSG0000003448620
Gbx1 / P82976 / Homeobox protein GBX-1 / Q14549* / gastrulation brain homeobox 1*ENSMUSG0000006772420
Meox1 / P32442 / Homeobox protein MOX-1 / P50221* / mesenchyme homeobox 1*ENSMUSG0000000149317
Evx2 / P49749 / Homeobox even-skipped homolog protein 2 / Q03828* / even-skipped homeobox 2*ENSMUSG0000000181517
Meox2 / P32443 / Homeobox protein MOX-2 / P50222* / mesenchyme homeobox 2*ENSMUSG0000003614416


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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