ENSMUSG00000050766


Mus musculus

Features
Gene ID: ENSMUSG00000050766
  
Biological name :Ear14
  
Synonyms : Ear14 / Mus musculus eosinophil-associated, ribonuclease A family, member 4 (Ear4), mRNA.
  
Possible biological names infered from orthology : P10153 / P12724 / ribonuclease A family member 2 / ribonuclease A family member 3 / RNASE2 / RNASE3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 51203391
Gene end: 51204338
  
Corresponding Affymetrix probe sets: 10414553 (MoGene1.0st)   1450615_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056293
Ensembl peptide - ENSMUSP00000153887
NCBI entrez gene - 503847     See in Manteia.
NCBI entrez gene - 53877     See in Manteia.
MGI - MGI:3528616
RefSeq - NM_001017422
RefSeq - NM_017389
RefSeq Peptide - NP_001017422
RefSeq Peptide - NP_059085
swissprot - F6YUX7
swissprot - Q5GAN2
Ensembl - ENSMUSG00000050766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P10153ENSG00000169385Homo sapiens
 P12724ENSG00000169397Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ear6 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000006214861
Rnase2a / ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 3* / ribonuclease A family member 2*ENSMUSG0000004722260
O35292 / Rnase2b / Ribonuclease 2B / RNASE3* / P10153* / P12724* / RNASE2* / ribonuclease A family member 3* / ribonuclease A family member 2*ENSMUSG0000005960660
Ear2 / P97425 / Eosinophil cationic protein 2 / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000007259659
Ear1 / P97426 / Eosinophil cationic protein 1 / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000007260159
Ear10 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000009016658
Rnase6 / ribonuclease, RNase A family, 6 / Q93091* / ribonuclease A family member k6*ENSMUSG0000002188038


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023411  Ribonuclease A, active site
 IPR023412  Ribonuclease A-domain
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IBA
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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