ENSMUSG00000072596


Mus musculus

Features
Gene ID: ENSMUSG00000072596
  
Biological name :Ear2
  
Synonyms : Ear2 / Eosinophil cationic protein 2 / P97425
  
Possible biological names infered from orthology : P10153 / P12724 / ribonuclease A family member 2 / ribonuclease A family member 3 / RNASE2 / RNASE3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 44102654
Gene end: 44103534
  
Corresponding Affymetrix probe sets: 10414262 (MoGene1.0st)   10419154 (MoGene1.0st)   10419156 (MoGene1.0st)   10598175 (MoGene1.0st)   1422411_s_at (Mouse Genome 430 2.0 Array)   1449846_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074386
NCBI entrez gene - 13587     See in Manteia.
MGI - MGI:108020
RefSeq - NM_007895
RefSeq Peptide - NP_031921
swissprot - P97425
swissprot - W0UVF7
Ensembl - ENSMUSG00000072596
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P10153ENSG00000169385Homo sapiens
 P12724ENSG00000169397Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ear10 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000009016694
Ear1 / P97426 / Eosinophil cationic protein 1 / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000007260191
Ear6 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000006214877
Rnase2a / ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 3* / ribonuclease A family member 2*ENSMUSG0000004722262
O35292 / Rnase2b / Ribonuclease 2B / RNASE3* / P10153* / P12724* / RNASE2* / ribonuclease A family member 3* / ribonuclease A family member 2*ENSMUSG0000005960659
Ear14 / Mus musculus eosinophil-associated, ribonuclease A family, member 4 (Ear4), mRNA. / RNASE3* / P10153* / P12724* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000005076658
Rnase6 / ribonuclease, RNase A family, 6 / Q93091* / ribonuclease A family member k6*ENSMUSG0000002188033


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023411  Ribonuclease A, active site
 IPR023412  Ribonuclease A-domain
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IBA
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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