ENSMUSG00000059606


Mus musculus

Features
Gene ID: ENSMUSG00000059606
  
Biological name :Rnase2b
  
Synonyms : O35292 / Ribonuclease 2B / Rnase2b
  
Possible biological names infered from orthology : P10153 / P12724 / ribonuclease A family member 2 / ribonuclease A family member 3 / RNASE2 / RNASE3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 51162260
Gene end: 51163018
  
Corresponding Affymetrix probe sets: 10414551 (MoGene1.0st)   1450616_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075074
NCBI entrez gene - 54159     See in Manteia.
MGI - MGI:1858598
RefSeq - NM_019398
RefSeq Peptide - NP_062271
swissprot - O35292
swissprot - W0UVC5
Ensembl - ENSMUSG00000059606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P10153ENSG00000169385Homo sapiens
 P12724ENSG00000169397Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnase2a / ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 3* / ribonuclease A family member 2*ENSMUSG0000004722271
Ear14 / Mus musculus eosinophil-associated, ribonuclease A family, member 4 (Ear4), mRNA. / RNASE3* / P10153* / P12724* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000005076660
Ear1 / P97426 / Eosinophil cationic protein 1 / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000007260160
Ear6 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000006214859
Ear2 / P97425 / Eosinophil cationic protein 2 / RNASE2* / RNASE3* / P10153* / P12724* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000007259659
Ear10 / P12724* / RNASE3* / P10153* / RNASE2* / ribonuclease A family member 2* / ribonuclease A family member 3*ENSMUSG0000009016656
Rnase6 / ribonuclease, RNase A family, 6 / Q93091* / ribonuclease A family member k6*ENSMUSG0000002188039


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023411  Ribonuclease A, active site
 IPR023412  Ribonuclease A-domain
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IBA
 molecular_functionGO:0004522 ribonuclease A activity IEA
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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