Manteia

ENSMUSG00000052974

Mus musculus

Features

Gene ID:	ENSMUSG00000052974

Biological name :	Cyp2f2

Synonyms :	Cyp2f2 / Cytochrome P450 2F2 / P33267

Possible biological names infered from orthology :	CYP2F1 / cytochrome P450 family 2 subfamily F member 1 / P24903

Species:	Mus musculus

Chr. number:	7
Strand:	1
Band:	A3
Gene start:	27119909
Gene end:	27133660

Corresponding Affymetrix probe sets:	10551293 (MoGene1.0st) 1448792_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000146037 Ensembl peptide - ENSMUSP00000003100 NCBI entrez gene - 13107 See in Manteia. MGI - MGI:88608 RefSeq - NM_007817 RefSeq Peptide - NP_031843 swissprot - A0A0U1RPL9 swissprot - P33267 Ensembl - ENSMUSG00000052974

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CYP2C9	ENSDARG00000101423	Danio rerio
CYP2F1	ENSG00000197446	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Cyp2g1 / cytochrome P450, family 2, subfamily g, polypeptide 1	ENSMUSG00000049685	54
P56654 / Cyp2c37 / Cytochrome P450 2C37 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000042248	53
Q91X77 / Cyp2c50 / Cytochrome P450 2C50 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000054827	53
Q6XVG2 / Cyp2c54 / Cytochrome P450 2C54 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000067225	53
Q64458 / Cyp2c29 / Cytochrome P450 2C29 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000003053	52
P56656 / Cyp2c39 / Cytochrome P450 2C39 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000025003	52
P56655 / Cyp2c38 / Cytochrome P450 2C38 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000032808	52
Cyp2c66 / cytochrome P450, family 2, subfamily c, polypeptide 66 / CYP2C9* / P33261* / P11712* / P10632* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P...	ENSMUSG00000067229	52
Cyp2c65 / cytochrome P450, family 2, subfamily c, polypeptide 65 / CYP2C9* / P33261* / P11712* / P10632* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P...	ENSMUSG00000067231	52
P15392 / Cyp2a4 / Cytochrome P450 2A4 / P11509* / Q16696* / P20853* / CYP2A7* / CYP2A6* / CYP2A13* / cytochrome P450 family 2 subfamily A member 7* / cytochrome P450 family 2 subfamily A m...	ENSMUSG00000074254	52
Cyp2a5 / CYP2A6* / CYP2A7* / Q16696* / P20853* / P11509* / CYP2A13* / cytochrome P450 family 2 subfamily A member 7* / cytochrome P450 family 2 subfamily A member 6* / cytochrome P450 famil...	ENSMUSG00000005547	51
Q9D816 / Cyp2c55 / Cytochrome P450 2C55 / P33260* / CYP2C18* / AL583836.1* / cytochrome P450 family 2 subfamily C member 18*	ENSMUSG00000025002	51
Cyp2c23 / cytochrome P450, family 2, subfamily c, polypeptide 23	ENSMUSG00000025197	51
Cyp2b10 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000030483	50
O55071 / Cyp2b19 / Cytochrome P450 2B19 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000066704	50
Cyp2c40 / CYP2C8* / CYP2C9* / P33261* / P11712* / P10632* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C member 8* / cytochrome P450 fami...	ENSMUSG00000025004	49
Cyp2b13 / cytochrome P450, family 2, subfamily b, polypeptide 13 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040583	49
Cyp2b23 / cytochrome P450, family 2, subfamily b, polypeptide 23 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040650	49
Cyp2b9 / P12790 / Cytochrome P450 2B9 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040660	49
P56593 / Cyp2a12 / Cytochrome P450 2A12	ENSMUSG00000060407	49

Protein motifs (from Interpro)

Interpro ID	Name
IPR001128	Cytochrome P450
IPR002401	Cytochrome P450, E-class, group I
IPR017972	Cytochrome P450, conserved site
IPR020469	Cytochrome P450, CYP2 family
IPR036396	Cytochrome P450 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0009636	response to toxic substance	IMP
biological_process	GO:0018931	naphthalene metabolic process	IEA
biological_process	GO:0018979	trichloroethylene metabolic process	IEA
biological_process	GO:0019373	epoxygenase P450 pathway	IBA
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0005789	endoplasmic reticulum membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031090	organelle membrane	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0004497	monooxygenase activity	IEA
molecular_function	GO:0005506	iron ion binding	IEA
molecular_function	GO:0008392	arachidonic acid epoxygenase activity	IBA
molecular_function	GO:0008395	steroid hydroxylase activity	IBA
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
molecular_function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA
molecular_function	GO:0019825	oxygen binding	IEA
molecular_function	GO:0020037	heme binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Fatty acids

Xenobiotics

CYP2E1 reactions

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0008874	decreased sensitivity to xenobiotics	"increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Smarcb1^tm1Sho/Smarcb1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * DBA/2J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr