ENSMUSG00000067229


Mus musculus

Features
Gene ID: ENSMUSG00000067229
  
Biological name :Cyp2c66
  
Synonyms : Cyp2c66 / cytochrome P450, family 2, subfamily c, polypeptide 66
  
Possible biological names infered from orthology : CYP2C19 / CYP2C8 / CYP2C9 / cytochrome P450 family 2 subfamily C member 19 / cytochrome P450 family 2 subfamily C member 8 / cytochrome P450 family 2 subfamily C member 9 / P10632 / P11712 / P33261
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 39113898
Gene end: 39187072
  
Corresponding Affymetrix probe sets: 10463023 (MoGene1.0st)   1429994_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120397
Ensembl peptide - ENSMUSP00000084487
NCBI entrez gene - 69888     See in Manteia.
MGI - MGI:1917138
RefSeq - NM_001011707
RefSeq Peptide - NP_001011707
swissprot - D6RJ25
swissprot - Q5GLZ0
Ensembl - ENSMUSG00000067229
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2C9ENSDARG00000101423Danio rerio
 CYP2C23bENSGALG00000005795Gallus gallus
 CYP2C45ENSGALG00000023925Gallus gallus
 CYP2C8ENSG00000138115Homo sapiens
 CYP2C9ENSG00000138109Homo sapiens
 P33261ENSG00000165841Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyp2c65 / cytochrome P450, family 2, subfamily c, polypeptide 65 / CYP2C9* / P33261* / P11712* / P10632* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P...ENSMUSG0000006723194
Q64458 / Cyp2c29 / Cytochrome P450 2C29 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000000305373
Q9D816 / Cyp2c55 / Cytochrome P450 2C55 / P33260* / CYP2C18* / AL583836.1* / cytochrome P450 family 2 subfamily C member 18*ENSMUSG0000002500270
P56655 / Cyp2c38 / Cytochrome P450 2C38 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000003280869
P56654 / Cyp2c37 / Cytochrome P450 2C37 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000004224869
Q91X77 / Cyp2c50 / Cytochrome P450 2C50 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000005482769
P56656 / Cyp2c39 / Cytochrome P450 2C39 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000002500368
Q6XVG2 / Cyp2c54 / Cytochrome P450 2C54 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...ENSMUSG0000006722568
Cyp2c40 / CYP2C8* / CYP2C9* / P33261* / P11712* / P10632* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C member 8* / cytochrome P450 fami...ENSMUSG0000002500463
Cyp2c23 / cytochrome P450, family 2, subfamily c, polypeptide 23ENSMUSG0000002519761
Q91W64 / Cyp2c70 / Cytochrome P450 2C70 ENSMUSG0000006061361
Cyp2e1 / Q05421 / Cytochrome P450 2E1 / P05181* / cytochrome P450 family 2 subfamily E member 1*ENSMUSG0000002547957
Cyp2b23 / cytochrome P450, family 2, subfamily b, polypeptide 23 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*ENSMUSG0000004065052
Cyp2g1 / cytochrome P450, family 2, subfamily g, polypeptide 1ENSMUSG0000004968552
P33267 / Cyp2f2 / Cytochrome P450 2F2 / CYP2F1* / P24903* / cytochrome P450 family 2 subfamily F member 1*ENSMUSG0000005297452
P15392 / Cyp2a4 / Cytochrome P450 2A4 / P11509* / Q16696* / P20853* / CYP2A7* / CYP2A6* / CYP2A13* / cytochrome P450 family 2 subfamily A member 7* / cytochrome P450 family 2 subfamily A m...ENSMUSG0000007425452
Cyp2a5 / CYP2A6* / CYP2A7* / Q16696* / P20853* / P11509* / CYP2A13* / cytochrome P450 family 2 subfamily A member 7* / cytochrome P450 family 2 subfamily A member 6* / cytochrome P450 famil...ENSMUSG0000000554751
Cyp2b10 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*ENSMUSG0000003048351
O55071 / Cyp2b19 / Cytochrome P450 2B19 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*ENSMUSG0000006670451
Cyp2b9 / P12790 / Cytochrome P450 2B9 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*ENSMUSG0000004066050


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IGI
 biological_processGO:0019373 epoxygenase P450 pathway IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0004497 monooxygenase activity ISO
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity IBA
 molecular_functionGO:0008395 steroid hydroxylase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0034875 caffeine oxidase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Xenobiotics
CYP2E1 reactions
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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