ENSMUSG00000059741


Mus musculus

Features
Gene ID: ENSMUSG00000059741
  
Biological name :Myl3
  
Synonyms : Myl3 / Myosin light chain 3 / P09542
  
Possible biological names infered from orthology : P08590
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F2
Gene start: 110741861
Gene end: 110769798
  
Corresponding Affymetrix probe sets: 10589602 (MoGene1.0st)   1427768_s_at (Mouse Genome 430 2.0 Array)   1427769_x_at (Mouse Genome 430 2.0 Array)   1428266_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142424
Ensembl peptide - ENSMUSP00000142791
Ensembl peptide - ENSMUSP00000142530
Ensembl peptide - ENSMUSP00000078715
NCBI entrez gene - 17897     See in Manteia.
MGI - MGI:97268
RefSeq - NM_010859
RefSeq Peptide - NP_034989
swissprot - A0A0G2JDW2
swissprot - A0A0G2JDM3
swissprot - P09542
Ensembl - ENSMUSG00000059741
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:163073ENSDARG00000099712Danio rerio
 MYL3ENSGALG00000005448Gallus gallus
 MYL3ENSG00000160808Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myl4 / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / P12829* / myosin light chain 4*ENSMUSG0000006108673
Myl1 / P05977 / Myosin light chain 1/3, skeletal muscle isoform / P05976* / myosin light chain 1*ENSMUSG0000006181669
Myl6b / Q8CI43 / Myosin light chain 6B / P14649*ENSMUSG0000003982462
Myl6 / Q60605 / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle / P60660* / myosin light chain 6*ENSMUSG0000009084152


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002026 regulation of the force of heart contraction IEA
 biological_processGO:0006942 regulation of striated muscle contraction IEA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0031672 A band IEA
 cellular_componentGO:0031674 I band IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020908 Myh3 / P13541 / Myosin-3 / P11055* / myosin heavy chain 3*  / complex / reaction
 ENSMUSG00000051747 Ttn / titin / A2ASS6 / Q8WZ42*  / complex
 ENSMUSG00000055775 Myh8 / P13542 / Myosin-8 / P13535* / myosin heavy chain 8*  / complex / reaction
 ENSMUSG00000061816 Myl1 / P05977 / Myosin light chain 1/3, skeletal muscle isoform / P05976* / myosin light chain 1*  / complex
 ENSMUSG00000040752 Myh6 / Q02566 / myosin, heavy polypeptide 6, cardiac muscle, alpha / P13533* / myosin heavy chain 6*  / complex / reaction
 ENSMUSG00000061086 Myl4 / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / P12829* / myosin light chain 4*  / complex
 ENSMUSG00000013936 Myl2 / P51667 / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform / P10916* / myosin light chain 2*  / complex
 ENSMUSG00000059741 Myl3 / P09542 / Myosin light chain 3 / P08590*  / complex
 ENSMUSG00000002100 Mybpc3 / myosin binding protein C, cardiac / Q14896*  / complex
 ENSMUSG00000020061 Mybpc1 / myosin binding protein C, slow type / Q00872*  / complex
 ENSMUSG00000038670 Mybpc2 / Q5XKE0 / Myosin-binding protein C, fast-type / Q14324*  / complex






 

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