ENSMUSG00000061559


Mus musculus

Features
Gene ID: ENSMUSG00000061559
  
Biological name :Wdr61
  
Synonyms : Q9ERF3 / Wdr61 / WD repeat domain 61
  
Possible biological names infered from orthology : Q9GZS3
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.3
Gene start: 54714735
Gene end: 54734519
  
Corresponding Affymetrix probe sets: 10593740 (MoGene1.0st)   1434433_x_at (Mouse Genome 430 2.0 Array)   1448102_a_at (Mouse Genome 430 2.0 Array)   1454954_at (Mouse Genome 430 2.0 Array)   1459985_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113560
Ensembl peptide - ENSMUSP00000123077
Ensembl peptide - ENSMUSP00000119362
Ensembl peptide - ENSMUSP00000056359
Ensembl peptide - ENSMUSP00000112811
NCBI entrez gene - 66317     See in Manteia.
MGI - MGI:1917493
RefSeq - NM_001025376
RefSeq - XM_011242785
RefSeq - NM_023191
RefSeq - NM_001025375
RefSeq Peptide - NP_001020546
RefSeq Peptide - NP_001020547
RefSeq Peptide - NP_075680
swissprot - Q9ERF3
swissprot - D6RDC7
swissprot - Q8BVQ0
swissprot - A0MNP4
swissprot - D6RJ72
Ensembl - ENSMUSG00000061559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr61ENSDARG00000007755Danio rerio
 WDR61ENSGALG00000003221Gallus gallus
 WDR61ENSG00000140395Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Katnb1 / Q8BG40 / Katanin p80 WD40 repeat-containing subunit B1 / Q9BVA0* / katanin regulatory subunit B1*ENSMUSG0000003178725
Wdr38 / Q9D994 / WD repeat domain 38 / Q5JTN6*ENSMUSG0000003529525
Poc1b / Q8BHD1 / POC1 centriolar protein B / Q8TC44*ENSMUSG0000001995222
Nle1 / Q8VEJ4 / Notchless protein homolog 1 / Q9NVX2* / notchless homolog 1*ENSMUSG0000002069222
Wdr5b / Q9D7H2 / WD repeat domain 5B / Q86VZ2*ENSMUSG0000003437922
Wdr5 / P61965 / WD repeat domain 5 / P61964*ENSMUSG0000002691721
Poc1a / Q8JZX3 / POC1 centriolar protein A / Q8NBT0*ENSMUSG0000002334520
P63005 / Pafah1b1 / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 / P43034* / platelet activating factor acetylhydrolase 1b regulatory subunit 1*ENSMUSG0000002074519
Q6PE01 / Snrnp40 / U5 small nuclear ribonucleoprotein 40 kDa protein / Q96DI7* / small nuclear ribonucleoprotein U5 subunit 40*ENSMUSG0000007408817
Daw1 / dynein assembly factor with WD repeats 1 / Q8N136*ENSMUSG0000005316113


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR024977  Anaphase-promoting complex subunit 4, WD40 domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter ISO
 biological_processGO:0045638 negative regulation of myeloid cell differentiation ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation ISS
 biological_processGO:0080182 histone H3-K4 trimethylation ISO
 biological_processGO:2001162 positive regulation of histone H3-K79 methylation ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016593 Cdc73/Paf1 complex ISO
 cellular_componentGO:0035327 transcriptionally active chromatin ISS
 cellular_componentGO:0055087 Ski complex ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
mRNA decay by 3 to 5 exoribonuclease
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019977 Hbs1l / Q69ZS7 / HBS1-like protein / Q9Y450* / HBS1 like translational GTPase*  / complex
 ENSMUSG00000040356 Skiv2l / superkiller viralicidic activity 2-like (S. cerevisiae) / Q15477* / Ski2 like RNA helicase*  / complex
 ENSMUSG00000061559 Wdr61 / Q9ERF3 / WD repeat domain 61 / Q9GZS3*  / complex
 ENSMUSG00000033991 Ttc37 / tetratricopeptide repeat domain 37 / Q6PGP7*  / complex






 

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